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[以致心律失常性右室发育不良患者为例探讨复发性室性心动过速的心电图治疗机会]

[Electrocardiologic opportunities for the treatment of recurrent ventricular tachycardia on the example of a patient with arrhythmogenic right ventricular dysplasia].

作者信息

Pudło Joanna, Senderek Tomasz, Lelakowska-Pieła Maria, Bednarek Jacek, Lelakowski Jacek

出版信息

Przegl Lek. 2014;71(6):355-8.

PMID:25344979
Abstract

Arrhythmogenic right ventricular dysplasia is a genetic disease, in which pathologic fibrofatty tissue occurs mainly in the right ventricle of the heart. Changes in heart muscle predispose to arrhythmias such as ventricular tachycardia or ventricular fibrillation, so these patients are candidates for implantation of implantable cardioverter-defibrillator. Furthermore, depending on the indication, RF-ablation is performed, which, due to changes in morphology of the heart muscle, are often difficult and of uncertain efficacy. In this paper we present a case of a patient with implanted cardioverter-defibrillator for primary prevention of sudden cardiac death. Initially, the patient experienced only complications related to the possession of the device, but due to the significant progression of the disease and symptoms, the device turned out to be necessary. In addition, the patient underwent complex electrophysiology procedures to control recurrent episodes of ventricular tachycardia. Treatment of cardiac arrhythmias in arrhythmogenic right ventricular dysplasia is problematic both because of the inability to predict the course of disease in asymptomatic patients, as well as due to the difficulty of carrying out effective ablation of arrhythmia foci in morphologically altered myocardium.

摘要

致心律失常性右室发育不良是一种遗传性疾病,其中心脏病理纤维脂肪组织主要出现在右心室。心肌的变化易引发心律失常,如室性心动过速或室颤,因此这些患者适合植入植入式心脏复律除颤器。此外,根据适应症,会进行射频消融,但由于心肌形态的改变,这种消融往往困难且疗效不确定。在本文中,我们介绍了一例植入心脏复律除颤器以一级预防心源性猝死的患者。起初,患者仅经历了与该装置相关的并发症,但由于疾病的显著进展和症状,该装置最终被证明是必要的。此外,患者还接受了复杂的电生理程序以控制室性心动过速的反复发作。致心律失常性右室发育不良的心律失常治疗存在问题,这既是因为无法预测无症状患者的疾病进程,也是因为在形态改变的心肌中难以有效消融心律失常病灶。

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