Wang Zhong-lei, Fu Ting-xia, Hu Ying-xin, Li Gui-ling, Mao De-hua, Tan Wen-bin
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2014 Jun;26(3):311-3, 319.
To study the changes of cerebral function and pathological morphology before and after the antiparasitic treatment with albendazole and praziquantel in patients with cerebral cysticercosis.
The data of EEG and neuroimaging of 412 patients with cerebral cysticercosis were retrospectively analyzed.
Before the treatment, the mild abnormality, moderate abnormality, and severe abnormality were observed in 40.53%, 45.63% and 13.84% of the patients respectively, which mainly showed the diffuse or focal irregular slow waves, or epileptiform discharges found in the abnormal brain waves. CT/MRI manifestation could be divided into six types, including single sacculus type (23.59%), multiple sacculus type (44.42%), encephalitis type (13.59%), coexistence of macrocyst and sacculus type (4.85%), calcification type (2.18%), and mixed type (11.41%). After 3 courses of the treatment, the normal and improved EEGs were observed in 79.85% and 20.15%, respectively. CT/MRI showed the foci being all absorbed (77.18%), being most absorbed (20.63%), and being no changes (20.18%) which were calcified focus. When cerebral cysticercosis were in acute stage (the single and multiple sacculus type, encephalitis type, and macrocyst and sacculus coexistence type), the therapeutic effect was good; while in the mixed type, the therapeutic effect was relatively poor. If cysticercosis were in the calcification stage, the patients only needed the heteropathy.
In the patients with cerebral cysticercosis, EEGs show the mild to severe abnormalities, and CT/MRI mainly shows the multiple sacculus type. After the treatment, the abnormal EEGs are gradually recovered and the low density foci can be all absorbed, but some calcified focus still exist in some patients.
研究脑囊尾蚴病患者使用阿苯达唑和吡喹酮进行抗寄生虫治疗前后脑功能及病理形态学的变化。
回顾性分析412例脑囊尾蚴病患者的脑电图和神经影像学资料。
治疗前，分别有40.53%、45.63%和13.84%的患者脑电图表现为轻度异常、中度异常和重度异常，主要表现为弥漫性或局灶性不规则慢波，或异常脑电波中出现癫痫样放电。CT/MRI表现可分为6种类型，包括单囊型（23.59%）、多囊型（44.42%）、脑炎型（13.59%）、大囊与囊共存型（4.85%）、钙化型（2.18%）和混合型（11.41%）。治疗3个疗程后，脑电图正常和改善的分别占79.85%和20.15%。CT/MRI显示病灶全部吸收（77.18%）、大部分吸收（20.63%）及无变化（20.18%，为钙化灶）。脑囊尾蚴病处于急性期（单囊和多囊型、脑炎型及大囊与囊共存型）时，治疗效果良好；而混合型治疗效果相对较差。若囊尾蚴病处于钙化期，患者仅需对症治疗。
脑囊尾蚴病患者脑电图表现为轻至重度异常，CT/MRI主要表现为多囊型。治疗后脑电图异常逐渐恢复，低密度病灶可全部吸收，但部分患者仍存在一些钙化灶。
