Marten-Mittag Birgitt, Book Katrin, Buchhold Britta, Dinkel Andreas, Gründobler Bärbel, Henrich Gerhard, Huber Birgit, Pirker Celia, Regenberg Anita, Schickel Simone, Senf Bianca, Wünsch Alexander, Herschbach Peter
Division of Psychosocial Oncology, Department of Psychosomatic Medicine and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Roman-Herzog Comprehensive Cancer Center, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Psychooncology. 2015 Jun;24(6):653-60. doi: 10.1002/pon.3708. Epub 2014 Oct 24.
The aim of this study is to validate the Basic Documentation for Psycho-Oncology Short Form (PO-Bado SF), a six item interview-based expert rating scale for distress screening in cancer patients.
Using a heterogeneous multicenter study sample (n = 1551), we examined validity, reliability, and dimensionality of the PO-Bado SF. The Hospital Anxiety and Depression Scale (HADS), the Distress Thermometer, the Questionnaire on Stress in Cancer, and the Patient Health Questionnaire were used to investigate convergent validity. Confirmatory factor analysis was applied to address unidimensionality. An optimal cutoff point was determined by ROC analysis and the maximum of Youden's index. An additional study with n = 41 audio recorded PO-Bado SF interviews was carried out to assess inter-rater reliability.
Mean age of the study sample was 64.0 (SD = 12.0), 42% were women. About 24% of the patients suffered from metastases. The one-factor solution was confirmed; internal consistency of the PO-Bado SF was high (α = 0.84). The PO-Bado SF total score correlated significantly with all psychosocial measures, the highest correlation was with the HADS total score (r = 0.64). Patients with severe disease conditions (metastases, psychological/psychiatric treatment in the past, low performance status) received higher distress ratings (p < 0.001). Using HADS total score (>13) as external criterion, an optimal PO-Bado SF cutoff score of >9 emerged (sensitivity 0.75; specificity 0.82). Inter-rater reliability was satisfactory for each of the six items (intra class correlation of 0.75 to 0.85).
The PO-Bado SF is a short, reliable and valid expert rating scale to identify distressed cancer patients.
本研究旨在验证心理肿瘤学简明基础文档(PO-Bado SF),这是一种基于六项访谈的专家评分量表,用于癌症患者的痛苦筛查。
我们使用异质性多中心研究样本(n = 1551),检验了PO-Bado SF的有效性、可靠性和维度。使用医院焦虑抑郁量表(HADS)、痛苦温度计、癌症应激问卷和患者健康问卷来研究收敛效度。应用验证性因子分析来确定单维度性。通过ROC分析和尤登指数的最大值确定最佳截断点。另外进行了一项包含41次PO-Bado SF访谈音频记录的研究,以评估评分者间信度。
研究样本的平均年龄为64.0(标准差 = 12.0),42%为女性。约24%的患者患有转移瘤。单因素解决方案得到确认;PO-Bado SF的内部一致性较高(α = 0.84)。PO-Bado SF总分与所有心理社会测量指标均显著相关,与HADS总分的相关性最高(r = 0.64)。患有严重疾病(转移瘤、过去接受过心理/精神治疗、低体能状态)的患者痛苦评分更高(p < 0.001)。以HADS总分(>13)作为外部标准,得出PO-Bado SF的最佳截断分数>9(敏感性0.75;特异性0.82)。六项中的每一项评分者间信度均令人满意(组内相关系数为0.75至0.85)。
PO-Bado SF是一种简短、可靠且有效的专家评分量表,用于识别痛苦的癌症患者。