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[有和无原发性高血压家族史儿童红细胞膜Ca2(+)-Mg2(+)-ATP酶活性的比较]

[Comparison of erythrocyte membrane Ca2(+)-Mg2(+)-ATPase activity in children with and without a family history of essential hypertension].

作者信息

Cheng H Y, Liu L S, Zheng D Y

出版信息

Zhonghua Xin Xue Guan Bing Za Zhi. 1989 Dec;17(6):321-3, 382.

PMID:2534656
Abstract

15 children with and without family history of essential hypertension respectively were chosen to compare erythrocyte membrane Ca2(+)-Mg2(+)-ATPase activity measured with biochemical method. Results were as follows: erythrocyte membrane Ca2(+)-Mg2(+)-ATPase activity was lower in children with family history of essential hypertension (2.16 +/- 1.10 vs 3.36 +/- 1.19 mumol Pi.mg protein-1/hour, P less than 0.01). This may be the cause of increase of intraerythrocyte calcium in offspring of hypertensive patients.

摘要

分别选取15名有和没有原发性高血压家族史的儿童，用生化方法比较测定红细胞膜钙-镁-ATP酶活性。结果如下：有原发性高血压家族史的儿童红细胞膜钙-镁-ATP酶活性较低（2.16±1.10对3.36±1.19μmol无机磷·毫克蛋白⁻¹/小时，P<0.01）。这可能是高血压患者后代红细胞内钙增加的原因。

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