Howland Robert H
J Psychosoc Nurs Ment Health Serv. 2014 Sep;52(9):13-5. doi: 10.3928/02793695-20140820-01. Epub 2014 Sep 4.
Atypical antipsychotic drugs are not all alike with respect to their pharmacologies, therapeutic uses, and side eff ects, although many clinicians lump them together and do not distinguish among them. Risk assessment for the potential use of a drug, such as aripiprazole (Abilify), should not focus on any particular adverse effect, but rather should consider risk assessment in a broader context. Specifically, what are the alternatives, and what are their inherent risk profiles? What is the risk of no treatment? Side eff ects commonly associated with a particular drug or class of drugs can also occur with other drugs. For any drug prescribed for any reason, prescribers should document discussion about common and potentially serious adverse effects, as well as document clinical monitoring. Alternative treatments and their inherent risks, along with the risks of not taking medication for a particular condition, should also be discussed with patients and documented.
非典型抗精神病药物在药理作用、治疗用途和副作用方面并非完全相同，尽管许多临床医生将它们归为一类，不加区分。对于潜在使用的药物，如阿立哌唑（安律凡）进行风险评估时，不应只关注任何特定的不良反应，而应在更广泛的背景下考虑风险评估。具体而言，有哪些替代药物，它们固有的风险状况如何？不治疗的风险是什么？与特定药物或药物类别通常相关的副作用也可能在其他药物中出现。对于因任何原因开具的任何药物，开处方者应记录关于常见和潜在严重不良反应的讨论情况，以及临床监测情况。还应与患者讨论替代治疗方法及其固有风险，以及不针对特定病症服药的风险，并记录下来。
