Hannhart B
Laboratoire de Physiopathologie respiratoire, INSERM, Vandoeuvre-lès-Nancy.
C R Seances Soc Biol Fil. 1989;183(5):419-27.
During light slow-wave sleep, ventilation is principally regulated by automatic metabolic control system. An instability in the respiratory control may be the predominant disturbance leading to very irregular or periodic breathing. During deep sleep, ventilation is progressively more stable. During REM sleep, automatic regulation is abolished and ventilation is particularly dependent on the compartmental control system. The reduction in airways and respiratory muscles tone favors the occurrence of obstructive apneas. The elevation in arousal threshold leads prolongation of the obstructive events.
在浅慢波睡眠期间,通气主要由自动代谢控制系统调节。呼吸控制的不稳定可能是导致非常不规则或周期性呼吸的主要干扰因素。在深度睡眠期间,通气逐渐变得更加稳定。在快速眼动睡眠期间,自动调节被取消,通气特别依赖于分区控制系统。气道和呼吸肌张力的降低有利于阻塞性呼吸暂停的发生。唤醒阈值的升高导致阻塞性事件的延长。