Furino Claudio, Cicinelli Maria Vittoria, Boscia Francesco, Alessio Giovanni
Ophthalmic Surg Lasers Imaging Retina. 2014 Nov-Dec;45(6):596-7. doi: 10.3928/23258160-20141008-03. Epub 2014 Oct 29.
The authors present the case of an idiopathic epiretinal membrane (ERM) secondary to an acute self-repaired macular microhole documented by optical coherence tomography (OCT). A 65-year-old phakic woman presenting with acute onset of light flashes, myodesopsia, and central negative scotoma in the right eye was diagnosed with age-related posterior vitreous detachment. Spectral-domain OCT showed a tiny defect of the outer retina, consistent with the diagnosis of macular microhole, which spontaneously closed after 4 weeks. Six months later, the patient developed a contracting ERM, and her visual acuity significantly worsened. This case represents the first in vivo documentation of retinal pigment epithelium cell migration through a macular microhole, highlighting the importance of OCT in understanding idiopathic ERM pathogenesis.
作者报告了一例特发性视网膜前膜（ERM）病例，该病例继发于光学相干断层扫描（OCT）记录的急性自愈性黄斑微裂孔。一名65岁有晶状体女性，右眼急性发作闪光、飞蚊症和中心性暗点，被诊断为年龄相关性后玻璃体脱离。频域OCT显示外层视网膜有一个微小缺损，符合黄斑微裂孔的诊断，该裂孔在4周后自发闭合。6个月后，患者出现收缩性ERM，视力显著下降。该病例是视网膜色素上皮细胞通过黄斑微裂孔迁移的首例体内记录，突出了OCT在理解特发性ERM发病机制中的重要性。
