University of Groningen, University Medical Center Groningen, Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), Groningen, The Netherlands,
Eur Child Adolesc Psychiatry. 2015 Aug;24(8):887-95. doi: 10.1007/s00787-014-0633-9. Epub 2014 Oct 28.
The following hypotheses were tested in a longitudinal, population-based study: (1) Attention deficit hyperactivity disorder (ADHD) symptoms are associated with peer dislike and victimisation; (2) Peer dislike and victimisation increase the risk for subsequent depression; and (3) The effect of ADHD symptoms on depression is partly mediated through peer dislike and victimisation. Gender differences in mediating pathways through peer dislike and victimisation to depression were additionally explored. The Child Behaviour Checklist (CBCL), Youth Self Report (YSR) and Teacher's Checklist of Pathology (TCP) assessed ADHD symptoms in 728 adolescents. Peer nominations were used to assess peer dislike and victimisation. The Composite International Diagnostic Interview (CIDI) was used to assess depression. Effects of peer dislike, victimisation, and ADHD symptoms on depression were modelled using Cox regression. ADHD symptoms were associated with peer dislike (rs = 0.17, p < 0.001) and victimisation (rs = 0.11, p = 0.001). Dislike, victimisation, and ADHD symptoms increased risk for depression. Risk for depression associated with victimisation and ADHD symptoms reduced with time. Dislike and victimisation mediated 7 % of the effect of ADHD symptoms on depression. Pathways through dislike and victimisation were present in girls but not in boys. Peer dislike and victimisation explain, to a limited extent, the prospective association between ADHD and depression, particularly in girls.
（1）注意力缺陷多动障碍（ADHD）症状与同伴反感和受害有关；（2）同伴反感和受害增加了随后抑郁的风险；（3）ADHD 症状对抑郁的影响部分通过同伴反感和受害来介导。此外，还探讨了性别差异在通过同伴反感和受害导致抑郁的中介途径中的作用。728 名青少年使用儿童行为检查表（CBCL）、青少年自我报告（YSR）和教师病理检查表（TCP）评估 ADHD 症状。同伴提名用于评估同伴反感和受害。使用复合国际诊断访谈（CIDI）评估抑郁。使用 Cox 回归模型评估同伴反感、受害和 ADHD 症状对抑郁的影响。ADHD 症状与同伴反感（rs = 0.17，p < 0.001）和受害（rs = 0.11，p = 0.001）有关。反感、受害和 ADHD 症状增加了抑郁的风险。与受害和 ADHD 症状相关的抑郁风险随着时间的推移而降低。反感和受害解释了 ADHD 症状对抑郁影响的 7%。在女孩中存在通过反感和受害的途径，但在男孩中不存在。同伴反感和受害在一定程度上解释了 ADHD 与抑郁之间的前瞻性关联，特别是在女孩中。
