Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK.
Wolfson Centre for Young People's Mental Health, Cardiff University, Cardiff, UK.
J Child Psychol Psychiatry. 2023 Jan;64(1):4-15. doi: 10.1111/jcpp.13678. Epub 2022 Aug 16.
Young people with neurodevelopmental disorders, such as attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), show high rates of mental health problems, of which depression is one of the most common. Given that depression in ASD and ADHD is linked with a range of poor outcomes, knowledge of how clinicians should assess, identify and treat depression in the context of these neurodevelopmental disorders is much needed. Here, we give an overview of the latest research on depression in young people with ADHD and ASD, including possible mechanisms underlying the link between ADHD/ASD and depression, as well as the presentation, assessment and treatment of depression in these neurodevelopmental disorders. We discuss the implications for clinicians and make recommendations for critical future research in this area.
患有神经发育障碍的年轻人，如注意力缺陷多动障碍（ADHD）和自闭症谱系障碍（ASD），表现出较高的心理健康问题发生率，其中抑郁是最常见的问题之一。鉴于 ASD 和 ADHD 中的抑郁与一系列不良后果相关，因此非常需要了解临床医生在这些神经发育障碍的背景下应如何评估、识别和治疗抑郁。在这里，我们概述了关于患有 ADHD 和 ASD 的年轻人的抑郁的最新研究，包括 ADHD/ASD 与抑郁之间的联系的潜在机制，以及这些神经发育障碍中抑郁的表现、评估和治疗。我们讨论了对临床医生的意义，并对该领域的关键未来研究提出了建议。
