Pôle Expertise Collective Inserm, Hôpital Paul Brousse (Villejuif), 94804 Villejuif, Cedex, France.
Expert Rev Anti Infect Ther. 2014 Dec;12(12):1441-61. doi: 10.1586/14787210.2014.976611. Epub 2014 Oct 28.
Antibacterial resistance is a worldwide threat, and concerns have arisen about the involvement of animal commensal and pathogenic bacteria in the maintenance and spread of resistance genes. However, beyond the facts related to the occurrence of resistant microorganisms in food, food-producing animals and companion animals and their transmission to humans, it is important to consider the vast environmental 'resistome', the selective pathways underlying the emergence of antibacterial resistance and how we can prepare answers for tomorrow.
抗菌耐药性是一个全球性的威胁,人们开始关注动物共生菌和致病菌在耐药基因的维持和传播中的作用。然而,除了与食品、食用动物和伴侣动物中耐药微生物的出现及其向人类传播相关的事实之外,还需要考虑到广泛的环境“耐药组”、抗菌耐药性产生的潜在选择途径,以及我们如何为明天做好准备。