Novák L, Půza V
Stomatologická klinika, Hradec Králové.
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl. 1989;32(4):353-63.
Cytopathological changes due to self-polymerizing enamel adhesives Evikrol Bond and Concise Enamel Bond were studied. Both the materials were toxic for in vitro cells. They caused death of the cells and degenerative changes appeared in some organelles including the cell membrane. This resulted in bad adhesion of the cells to the substrate. Extractions of these adhesives caused also changes in the karyoplasm. The observed change of epithelioid HEp-2 permanent line cells into fibroblastoid cells requires, however, further verification by means of special tests.
研究了自聚合牙釉质粘合剂Evikrol Bond和Concise Enamel Bond引起的细胞病理学变化。这两种材料对体外细胞均有毒性。它们导致细胞死亡,一些细胞器包括细胞膜出现退行性变化。这导致细胞与底物的粘附性差。这些粘合剂的提取物也引起核质变化。然而,观察到的上皮样HEp-2永久系细胞向成纤维样细胞的转变需要通过特殊测试进一步验证。