Trial J
Department of Immunology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
Reg Immunol. 1989 Jan-Feb;2(1):14-21.
Human T cells activated by antigen in vitro mediated both the 2-hour and 24-hour phases of delayed-type hypersensitivity (DTH) when transferred into the mouse footpad. The passively transferred human DTH was similar to murine DTH by kinetics, vasoactive amine dependence, and histologic criteria. These results offer a functional assay for determining whether human T cells are activated by viral or tumor antigens.
体外被抗原激活的人T细胞转移至小鼠足垫后，可介导迟发型超敏反应（DTH）的2小时和24小时阶段。被动转移的人DTH在动力学、血管活性胺依赖性和组织学标准方面与鼠DTH相似。这些结果提供了一种功能测定方法，用于确定人T细胞是否被病毒或肿瘤抗原激活。
