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164例孕24至28周出生婴儿的预后预测。

Prediction of outcome in 164 infants born after 24 to 28 weeks gestation.

作者信息

Eg-Andersen G

机构信息

Department of Neonatology, Rigshospitalet, Copenhagen, Denmark.

出版信息

Acta Paediatr Scand Suppl. 1989;360:56-61.

PMID:2534979
Abstract

Between 1984 and 1987 164 infants born after 24 to 28 completed weeks were admitted to our unit. In 6 children respirator treatment was withdrawn between days 6 and 57 mainly on the basis of severe intracranial bleeding and periventricular leucomalacia. Among 102 (62%) surviving infants, 18 (18%) had a major handicap (cerebral palsy, IQ less than 50, blindness) at follow-up, in 6 of the 18 (6%) there was a combination of several major handicaps. We conclude that we can still not reliably predict serious handicap and we are therefore faced with a serious ethical dilemma which we think can best be approached in a trust-relationship between parents and staff.

摘要

1984年至1987年间,164名在妊娠24至28足周后出生的婴儿被收治入我们科室。6名儿童在出生后第6天至第57天期间停止了呼吸支持治疗,主要原因是严重的颅内出血和脑室周围白质软化。在102名(62%)存活的婴儿中,18名(18%)在随访时存在严重残疾(脑瘫、智商低于50、失明),其中18名中有6名(6%)存在多种严重残疾。我们得出结论,我们仍然无法可靠地预测严重残疾,因此我们面临着一个严重的伦理困境,我们认为最好通过父母与医护人员之间的信任关系来解决。

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Prediction of outcome in 164 infants born after 24 to 28 weeks gestation.164例孕24至28周出生婴儿的预后预测。
Acta Paediatr Scand Suppl. 1989;360:56-61.
2
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引用本文的文献

1
Evidence of selection bias in preterm survival studies: a systematic review.早产生存研究中选择偏倚的证据:一项系统综述。
Arch Dis Child Fetal Neonatal Ed. 2001 Mar;84(2):F79-84. doi: 10.1136/fn.84.2.f79.
2
Perinatal management at the lower margin of viability.极低出生体重儿的围产期管理
Arch Dis Child Fetal Neonatal Ed. 1996 May;74(3):F214-8. doi: 10.1136/fn.74.3.f214.