Ugrinov R
Stomatologiia (Sofiia). 1989 Jan-Feb;71(1):64-8.
The possible risk factors originating during surgical stomatological interventions of patients on anticoagulant therapy are described in the paper. They are connected both with the main disease the reason the patient is on such a therapy and with the intake of anticoagulants being of two kinds; direct (physiological) and indirect. Two patients are described: one with prosthetization in 1982 with aorta prosthesis because of aortic valvular defect and a female patient with lupus eythematodes disseminata and severe organ disorders resulting from that (cardiac, renal, amputation of the left arm). Both patients were on maintenance therapy with indirect coagulants: sincoumar and sintrom. The author describes the pre-operation treatment, mode of anticoagulant dosing during and after the surgical intervention and the agents used for local hemostasis and antibiotic protection. Hemorrhagic complications were not observed in the patients described. Based on literature data and the patients described, the authors takes the liberty to sum up the tendencies in the behaviour of the stomatologist during surgical sanation of oral cavity of patients, on anticoagulant therapy.
本文描述了接受抗凝治疗的患者在口腔外科手术干预过程中可能出现的风险因素。这些因素既与患者接受此类治疗的主要疾病有关，也与两种抗凝剂的摄入有关，即直接（生理性）抗凝剂和间接抗凝剂。文中描述了两名患者：一名在1982年因主动脉瓣缺陷接受主动脉假体修复手术；另一名女性患者患有播散性红斑狼疮，并由此导致严重的器官功能障碍（心脏、肾脏问题以及左臂截肢）。两名患者均接受间接抗凝剂维持治疗，药物分别为新双香豆素和醋硝香豆素。作者描述了术前治疗、手术干预期间及术后抗凝剂的给药方式，以及用于局部止血和抗生素防护的药物。在所描述的患者中未观察到出血并发症。基于文献数据和所描述的患者情况，作者冒昧总结了口腔外科医生在为接受抗凝治疗的患者进行口腔手术治疗时的行为倾向。
