Wilhelm M, Lombeck I, Hafner D, Ohnesorge F K
Institut für Toxikologie, Universität Düsseldorf, Fed. Rep. of Germany.
J Trace Elem Electrolytes Health Dis. 1989 Sep;3(3):165-70.
Hair lead (PbH) levels were measured in 474 children, aged 3-7 years, living in an industrialized (Duisburg) and in a rural area (Westphalia) of the F.R.G. by atomic absorption spectrometry. PbH values were log-normally distributed. All mean concentrations are therefore given as geometric means. The overall mean PbH content was 2.7 mg/kg. In the summer PbH levels were higher than in the winter (3.8 vs. 1.4 mg/kg) and the values from the urban children were higher compared with those from rural children (3.7 vs. 1.9 mg/kg). Boys had more Pb in their hair than girls (3.9 vs. 2.0 mg/kg) and PbH levels decreased between the 4th and 7th year. In the industrialized area the PbH content of children whose fathers were factory workers, was higher than that of children whose fathers had other occupations (4.2 vs. 3.0 mg/kg). Non-German children had more Pb in their hair than German children (5.2 vs. 3.6 mg/kg). Pb content in the soil from the Duisburg area was related to PbH concentrations (R = 0.34). Since our observations are in line with the results of similar studies which used blood samples to monitor Pb exposure in children, we conclude that by using standardized conditions hair analysis is a valuable screening method.
采用原子吸收光谱法,对居住在德意志联邦共和国工业化地区(杜伊斯堡)和农村地区(威斯特法伦)的474名3至7岁儿童的发铅(PbH)水平进行了测量。PbH值呈对数正态分布。因此,所有平均浓度均以几何平均值表示。总体平均PbH含量为2.7毫克/千克。夏季的PbH水平高于冬季(3.8对1.4毫克/千克),城市儿童的值高于农村儿童(3.7对1.9毫克/千克)。男孩头发中的铅含量高于女孩(3.9对2.0毫克/千克),且在4至7岁之间PbH水平下降。在工业化地区,父亲为工厂工人的儿童的PbH含量高于父亲从事其他职业的儿童(4.2对3.0毫克/千克)。非德国儿童头发中的铅含量高于德国儿童(5.2对3.6毫克/千克)。杜伊斯堡地区土壤中的铅含量与PbH浓度相关(R = 0.34)。由于我们的观察结果与使用血样监测儿童铅暴露的类似研究结果一致,我们得出结论,在标准化条件下,头发分析是一种有价值的筛查方法。