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儿童食管炎性肌纤维母细胞瘤:一例报告并文献复习

Inflammatory myofibroblastic tumor of the esophagus in childhood: a case report and a review of the literature.

作者信息

Dousek Robert, Tuma Jiri, Planka Ladislav, Husek Karel, Sterba Jaroslav, Penka Igor

机构信息

Departments of *Pediatric Surgery †Pathology ‡Pediatric Oncology §Surgery, The University Hospital Brno, Brno, Czech Republic.

出版信息

J Pediatr Hematol Oncol. 2015 Mar;37(2):e121-4. doi: 10.1097/MPH.0000000000000275.

Abstract

Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal disease of low malignancy consisting of inflammatory cells inside a mesenchymal stroma comprising myofibroblasts. Biological behavior is variable, recurrence is uncommon, metastatic disease is rare. Treatment strategy is based on the status of low-grade malignant tumor. Radical surgery is considered to be the principal treatment modality, except if it requires a mutilating procedure. Only 6 cases of pediatric patients treated for IMT of the esophagus have been reported in English-language literature. Herein, a case of a 13-year-old boy with an IMT of the esophagus is presented.

摘要

炎性肌纤维母细胞瘤(IMT)是一种罕见的低恶性间叶性疾病,由包含肌成纤维细胞的间叶基质内的炎性细胞组成。生物学行为多变,复发不常见,转移性疾病罕见。治疗策略基于低级别恶性肿瘤的状况。除了需要进行致残性手术外,根治性手术被认为是主要的治疗方式。英文文献中仅报道了6例接受食管IMT治疗的儿科患者。本文介绍了1例13岁患有食管IMT的男孩病例。

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