Wang Guofei, Wang Shuhong, Jiang Pinglan, Zeng Chun
Department of Cardiothoracic Surgery ICU, Xiangya Hospital, Central South University, Changsha 410008, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2014 Oct;39(10):1077-82. doi: 10.11817/j.issn.1672-7347.2014.10.016.
To evaluate the condition of cancer-related fatigue (CRF) in breast cancer patients with chemotherapy and to explore the effect of Yoga on it.
After the completion of Yoga, 100 breast cancer patients with CRF (CFS>0) were selected and were randomly divided into the Yoga group and the control group (n=50). Patients in the control group only received routine cure and care while patients in the Yoga group received extra Yoga exercise, lasting for 4 months. Cancer fatigue scale (CFS) was evaluated in the 2nd, 4th and 6th round of chemotherapy.
At the end, 82 cases qualified for the study, 42 cases for the control group and 40 for the Yoga group. The mean score of body fatigue was 12.67±3.46. There was no significant difference in CRF between the Yago group and the control group before the Yoga intervention (P>0.05). After the 4th round of chemotherapy, the mean scores of CFS and body fatigue in the Yoga group were significantly lower than that in the control group (P<0.05). After the 6th round of chemotherapy, the mean scores of CFS, body fatigue and cognitive fatigue in the Yoga group were lower than that in the control group (P<0.05). Repeated analysis of variance showed that the difference in the overall fatigue, body fatigue and cognitive fatigue between the Yoga group and the control group was significant (P<0.05); the time influence on the overall fatigue, body fatigue and emotional fatigue was significant difference between the 2 groups (P<0.05); there were interactions between the effect of Yago and time on the overall fatigue, body fatigue and cognitive fatigue (P<0.05).
The body fatigue was more serious in breast cancer patients with chemotherapy. Yoga intervention could significantly reduce body fatigue, cognitive fatigue, thus reduce the overall fatigue in breast cancer patients with chemotherapy.
评估乳腺癌化疗患者癌症相关疲劳(CRF)状况,并探讨瑜伽对其的影响。
完成瑜伽训练后,选取100例CRF(CFS>0)乳腺癌患者,随机分为瑜伽组和对照组(n=50)。对照组患者仅接受常规治疗和护理,瑜伽组患者额外进行瑜伽锻炼,持续4个月。在第2、4和6轮化疗时评估癌症疲劳量表(CFS)。
最终,82例患者符合研究条件,对照组42例,瑜伽组40例。身体疲劳平均评分为12.67±3.46。瑜伽干预前,瑜伽组和对照组的CRF无显著差异(P>0.05)。第4轮化疗后,瑜伽组的CFS和身体疲劳平均评分显著低于对照组(P<0.05)。第6轮化疗后,瑜伽组的CFS、身体疲劳和认知疲劳平均评分低于对照组(P<0.05)。重复方差分析显示,瑜伽组和对照组在总体疲劳、身体疲劳和认知疲劳方面的差异有统计学意义(P<0.05);时间对两组总体疲劳、身体疲劳和情绪疲劳的影响有显著差异(P<0.05);瑜伽与时间对总体疲劳、身体疲劳和认知疲劳的影响存在交互作用(P<0.05)。
乳腺癌化疗患者身体疲劳更严重。瑜伽干预可显著减轻身体疲劳、认知疲劳,从而降低乳腺癌化疗患者的总体疲劳。