Koch Kevin M, Koff Matthew F, Shah Parina H, Kanwischer Adriana, Gui Dawei, Potter Hollis G
Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Magn Reson Med. 2015 Nov;74(5):1349-55. doi: 10.1002/mrm.25518. Epub 2014 Nov 3.
It has previously been demonstrated that increased overlap of spectral bins in three-dimensional multispectral imaging techniques (3D-MSI) can aid in reducing residual artifacts near metal implants. However, increasing spectral overlap also necessitates consideration of saturation effects for species with long T1 values. Here, an interleaved spectral bin acquisition strategy is presented for overlapping 3D-MSI that allows for flexible choice of repetition times while simultaneously addressing these cross talk concerns.
A phantom imaging experiment is used to illustrate the amplified effect of cross talk on 3D-MSI acquisitions. A methodological approach to address cross talk across a variety of prescribed repetition times is then described. Using the presented principles, a clinical subject with a total hip replacement was imaged to generate T1, proton density, and short-tau inversion recovery contrasts. In addition, a fracture instrumentation case was imaged pre- and postcontrast using T1-weighted spectrally overlapped 3D-MSI.
Phantom results demonstrate that conventional spectral interleaving approaches can generate unwanted signal characteristics in heavily overlapped 3D-MSI. Clinical images using the presented methods successfully demonstrate T1, proton density, and inversion recovery image contrasts using heavily overlapped 3D-MSI.
Through automated management of spectral bin distributions across multiple interleaves, a variety of longitudinal magnetization contrasts can efficiently be acquired without any clinically relevant cross-talk impact using heavily overlapped 3D-MSI.
先前已证明,三维多光谱成像技术(3D-MSI)中光谱 bins 重叠的增加有助于减少金属植入物附近的残余伪影。然而,增加光谱重叠也需要考虑具有长 T1 值的物质的饱和效应。在此,提出了一种用于重叠 3D-MSI 的交错光谱 bin 采集策略,该策略允许灵活选择重复时间,同时解决这些串扰问题。
使用体模成像实验来说明串扰对 3D-MSI 采集的放大效应。然后描述了一种在各种规定重复时间内解决串扰的方法。利用所提出的原理,对一名全髋关节置换的临床受试者进行成像,以生成 T1、质子密度和短 tau 反转恢复对比。此外,使用 T1 加权光谱重叠 3D-MSI 对一例骨折内固定病例进行了对比前后成像。
体模结果表明,传统的光谱交错方法在高度重叠的 3D-MSI 中会产生不需要的信号特征。使用所提出方法的临床图像成功地利用高度重叠的 3D-MSI 展示了 T1、质子密度和反转恢复图像对比。
通过对多个交错中的光谱 bin 分布进行自动管理,可以使用高度重叠的 3D-MSI 有效获取各种纵向磁化对比,而不会产生任何临床相关的串扰影响。