SEMAC-VAT 和 MSVAT-SPACE 序列策略在 1.5T 磁共振成像中减少金属伪影。

SEMAC-VAT and MSVAT-SPACE sequence strategies for metal artifact reduction in 1.5T magnetic resonance imaging.

机构信息

Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Invest Radiol. 2012 May;47(5):267-76. doi: 10.1097/RLI.0b013e318240a919.

Abstract

OBJECTIVES

To evaluate the ability of four magnetic resonance imaging (MRI) techniques to correct for metallic artifacts. These techniques consisted of 3 2D techniques and one 3D technique. In 2D imaging the techniques View Angle Tilting (VAT), Slice Encoding for Metal Artifact Correction (SEMAC) and a technique that employed a combination of the first two (SEMAC-VAT) were evaluated. In 3D imaging the technique Multiple Slab acquisition with VAT based on a SPACE sequence was evaluated (MSVAT-SPACE).

MATERIALS AND METHODS

Agarose phantoms and tissue phantoms with two commonly used metal implants (stainless steel and titanium) as well as two volunteers with metal implants were imaged at 1.5T. All phantoms and volunteers were imaged using VAT, SEMAC, SEMAC-VAT and MSVAT-SPACE techniques, as well as 2D and 3D conventional imaging techniques. Each technique was optimized for different image contrast mechanisms. Artifact reduction was quantitatively assessed in the agarose phantoms by volumetric measurement. Image quality was qualitatively assessed by blinded reads employing two readers. Each reader independently viewed the tissue phantom images and in vivo human images. Statistical analysis was performed using a Friedman test, Wilcoxon test and weighted Cohen's kappa test.

RESULTS

T1-weighted, T2-weighted, PD-weighted and STIR image contrasts were successfully implemented with the evaluated artifact reduction sequences in both the phantom experiments and in vivo images. For all evaluated image contrasts and both metal implants, a reduction in the volume of metal artifacts was seen when compared with 2D conventional acquisitions. The 2D metal artifact volumes on average were reduced by 49% ± 16%, 56% ± 15% and 63% ± 15% for VAT, SEMAC and SEMAC-VAT acquisitions respectively. When Friedman and Wilcoxon tests were applied the difference in metal artifact volume was found to be statistically significant when VAT, SEMAC and SEMAC-VAT were compared with the 2D conventional techniques. In 3D imaging on average MSVAT-SPACE reduced metal artifact volume compared with the 3D conventional imaging technique by 72% ± 23% for all evaluated image contrasts and both metal implants. The metal artifact volume differences were statistically significant when MSVAT-SPACE was compared with the 3D conventional technique. The blinded reads demonstrated that SEMAC-VAT and MSVAT-SPACE had distinctly superior quality compared with conventional acquisitions. Quality was measured in terms of artifact size, distortions, image quality and visualization of bone marrow and soft tissues adjacent to metal implants. This was the case for both tissue phantom images and human images with good interobserver agreement.

CONCLUSIONS

SEMAC-VAT (2D) and MSVAT-SPACE (3D) demonstrated a consistent, marked reduction of metal artifacts for different metal implants and offered flexible image contrasts (T1, T2, PD and STIR) with high image quality. These techniques likely will improve the evaluation of postoperative patients with metal implants.

摘要

目的

评估四种磁共振成像(MRI)技术纠正金属伪影的能力。这些技术包括 3 种 2D 技术和 1 种 3D 技术。在 2D 成像中,评估了三种技术,分别是视角倾斜(VAT)、用于金属伪影校正的切片编码(SEMAC)以及结合前两种技术的一种技术(SEMAC-VAT)。在 3D 成像中,评估了一种基于空间选择性激励(SPACE)序列的多层面采集技术,名为 VAT 基础的多层面采集(MSVAT-SPACE)(图 1)。

材料与方法

在 1.5T 磁共振扫描仪上对琼脂糖体模和含有两种常用金属植入物(不锈钢和钛)的组织体模以及两名带有金属植入物的志愿者进行成像。所有体模和志愿者均使用 VAT、SEMAC、SEMAC-VAT 和 MSVAT-SPACE 技术以及 2D 和 3D 常规成像技术进行扫描。每种技术都针对不同的图像对比机制进行了优化。在琼脂糖体模中,通过体积测量对金属伪影的减少进行了定量评估。通过两名观察者的盲法阅读对图像质量进行了定性评估。使用 Friedman 检验、Wilcoxon 检验和加权 Cohen's kappa 检验对数据进行了统计学分析。

结果

在体模实验和体内图像中,成功实现了评估的金属伪影校正序列的 T1 加权、T2 加权、PD 加权和 STIR 图像对比。与 2D 常规采集相比,所有评估的图像对比和两种金属植入物的金属伪影体积均减少。VAT、SEMAC 和 SEMAC-VAT 采集的平均金属伪影体积分别减少了 49%±16%、56%±15%和 63%±15%。当应用 Friedman 和 Wilcoxon 检验时,发现 VAT、SEMAC 和 SEMAC-VAT 与 2D 常规技术相比,金属伪影体积的差异具有统计学意义。在 3D 成像中,MSVAT-SPACE 平均比 3D 常规成像技术减少了 72%±23%的金属伪影体积,用于所有评估的图像对比和两种金属植入物。当将 MSVAT-SPACE 与 3D 常规技术进行比较时,金属伪影体积的差异具有统计学意义。盲法阅读表明,与常规采集相比,SEMAC-VAT 和 MSVAT-SPACE 的质量明显更好。质量是通过评估伪影大小、失真、图像质量以及金属植入物周围骨髓和软组织的可视化程度来衡量的。这对于组织体模图像和具有良好观察者间一致性的人体图像都是如此。

结论

SEMAC-VAT(2D)和 MSVAT-SPACE(3D)对不同的金属植入物表现出一致的、明显的金属伪影减少,并提供了具有高图像质量的灵活图像对比(T1、T2、PD 和 STIR)。这些技术可能会提高对带有金属植入物的术后患者的评估水平。

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