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A report on the co-occurrence of JAK2V617F and CALR mutations in myeloproliferative neoplasm patients.

作者信息

Xu Na, Ding Li, Yin Changxin, Zhou Xuan, Li Lin, Li Yulin, Lu Qisi, Liu Xiao-li

机构信息

Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou Dadao North Street No. 1838, Guangzhou, 510515, People's Republic of China.

出版信息

Ann Hematol. 2015 May;94(5):865-7. doi: 10.1007/s00277-014-2248-0. Epub 2014 Nov 5.

DOI:10.1007/s00277-014-2248-0
PMID:25366168
Abstract
摘要

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A report on the co-occurrence of JAK2V617F and CALR mutations in myeloproliferative neoplasm patients.一份关于骨髓增殖性肿瘤患者中JAK2V617F和CALR突变共现情况的报告。
Ann Hematol. 2015 May;94(5):865-7. doi: 10.1007/s00277-014-2248-0. Epub 2014 Nov 5.
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JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation.JAK2V617F 而非 CALR 突变通过 JAK1/STAT1 激活赋予对干扰素-α更高的分子反应。
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Coexistence of lymphoproliferative and myeloproliferative neoplasms with simultaneous CALR and JAK2 V617F mutations.伴有CALR和JAK2 V617F同时突变的淋巴增殖性和骨髓增殖性肿瘤共存
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[Application of genetic data to clinical practice of MPN].[遗传数据在骨髓增殖性肿瘤临床实践中的应用]
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Genetic and Clinical Characteristics of Patients with Philadelphia-Negative Myeloproliferative Neoplasm Carrying Concurrent Mutations in , and .携带 、 和 同时突变的费城阴性骨髓增殖性肿瘤患者的遗传和临床特征。
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JAK2 unmutated erythrocytosis: current diagnostic approach and therapeutic views.
JAK2 未突变红细胞增多症：当前的诊断方法和治疗观点。
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Archived bone marrow smears are an excellent source for NGS-based mutation detection in acute myeloid leukemia.存档的骨髓涂片是急性髓系白血病基于二代测序（NGS）的突变检测的极佳来源。
Leukemia. 2020 Aug;34(8):2220-2224. doi: 10.1038/s41375-020-0744-x. Epub 2020 Feb 14.
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Absence of CALR mutations in JAK2-negative polycythemia.JAK2阴性真性红细胞增多症中无CALR突变。
Haematologica. 2017 Jan;102(1):e15-e16. doi: 10.3324/haematol.2016.154799. Epub 2016 Oct 6.
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Coexisting JAK2V617F and CALR Exon 9 Mutation in Essential Thrombocythemia.原发性血小板增多症中JAK2V617F和CALR外显子9突变共存
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Analysis of phenotype and outcome in essential thrombocythemia with CALR or JAK2 mutations.伴有CALR或JAK2突变的原发性血小板增多症的表型与预后分析。
Haematologica. 2015 Jul;100(7):893-7. doi: 10.3324/haematol.2014.118299. Epub 2015 May 1.