Ali Mohammad Javed, Kamal Saurabh, Gupta Adit, Ali Mohammad Hasnat, Naik Milind N
Dacryology Service, L.V. Prasad Eye Institute, Hyderabad, India.
Int Forum Allergy Rhinol. 2015 Feb;5(2):174-7. doi: 10.1002/alr.21435. Epub 2014 Nov 3.
The aim of this study was to report the comparative clinical profiles and outcomes of simple and complex congenital nasolacrimal duct obstruction (CNLDO).
The study was a retrospective chart review of all patients presenting with CNLDO from a single surgeon's (M.J.A.) database. All patients underwent irrigation and probing under nasal endoscopic guidance. A detailed lacrimal system evaluation was performed, intraoperative findings including nasal endoscopy were documented, and etiologies of complex CNLDO were noted. Outcome measures were comparative profiles, and anatomical success and functional success of the interventions. Statistical analyses were performed using the Shapiro-Wilk test, Fisher's exact test, and Wilcoxon rank sum test.
Ninety-five eyes of 81 patients with simple CNLDO and 100 eyes of 83 patients with complex CNLDO were compared. The mean age at presentation was 17.6 months in simple CNLDO and 45.6 months in complex cases (p < 0.001). Epiphora and discharge were the most common symptoms; 89.4% among simple cases and 92% in the complex group. The most common causes of complex CNLDO were bony obstructions (23%), craniofacial syndromes (12%), and buried probe (10%). At a mean follow-up of 5.85 months for simple CNLDO and 4.68 months for complex CNLDO, anatomical success and functional success was noted in 97.8% and 94.7%, respectively, in simple CNLDO, and in 58% and 51%, respectively, in complex CNDLO (p < 0.001).
Bony obstruction, craniofacial syndrome, and buried probe were the most common reasons for a complex CNLDO, noted commonly in older children, with irrigation and probing having much poorer outcomes when compared with simpler obstructions.
本研究旨在报告单纯性和复杂性先天性鼻泪管阻塞(CNLDO)的临床特征及治疗结果并进行比较。
本研究是一项回顾性图表审查,数据来自一位外科医生(M.J.A.)数据库中所有患有CNLDO的患者。所有患者均在鼻内镜引导下进行冲洗和探通。对泪道系统进行了详细评估,记录术中发现,包括鼻内镜检查结果,并记录复杂性CNLDO的病因。观察指标为临床特征比较、干预措施的解剖学成功率和功能成功率。采用Shapiro-Wilk检验、Fisher精确检验和Wilcoxon秩和检验进行统计学分析。
比较了81例单纯性CNLDO患者的95只眼和83例复杂性CNLDO患者的100只眼。单纯性CNLDO患者就诊时的平均年龄为17.6个月,复杂性病例为45.6个月(p<0.001)。溢泪和分泌物增多是最常见的症状;单纯性病例中占89.4%,复杂性组中占92%。复杂性CNLDO最常见的原因是骨性阻塞(23%)、颅面综合征(12%)和探针埋置(10%)。单纯性CNLDO的平均随访时间为5.85个月,复杂性CNLDO为4.68个月,单纯性CNLDO的解剖学成功率和功能成功率分别为97.8%和94.7%,复杂性CNLDO分别为58%和51%(p<0.001)。
骨性阻塞、颅面综合征和探针埋置是复杂性CNLDO最常见的原因,多见于大龄儿童,与较简单的阻塞相比,冲洗和探通的治疗效果要差得多。