Heichel Jens, Struck Hans-Gert, Fiorentzis Miltiadis, Hammer Thomas, Bredehorn-Mayr Timm
Department of Ophthalmology, University Hospital of Martin Luther University Halle/Wittenberg, Halle (Saale), Germany.
Adv Ther. 2017 May;34(5):1221-1232. doi: 10.1007/s12325-017-0517-8. Epub 2017 Mar 24.
Congenital nasolacrimal duct obstruction (CNLDO) is the most common cause of epiphora in infancy. Spontaneous resolution occurs in the majority of the cases by 1 year of age. Nevertheless, obstruction has a negative impact on the outcome of conservative or surgical therapy, especially in cases of complex CNLDO. When the condition persists beyond several months, early intervention with dacryoendoscopy (DE) around the age of 1 year could yield good results. The objective of the study is to analyze the success rate and effectiveness of early DE for complex CNLDO in the first year of life.
A retrospective, non-comparative case series is presented. DE was performed under general anesthesia in patients between the age of 1 and 12 months with severe recurrent acute or chronic dacryocystitis. The medical histories, intraoperative and postoperative results after 3 months as well as via parents' interviews were analyzed to investigate the success rate.
A total of 18 consecutive DE in 16 patients between the age of 1 and 12 months (mean 7.3 ± 3.4 months) were studied. Nine lacrimal ducts were diagnosed with persistent chronic dacryocystitis refractory to probing/syringing. The remaining 9 presented recurrent acute dacryocystitis. Diagnostic DE was performed in 18 cases. A therapeutic DE was conducted in 15 lacrimal ducts (83.3%) with simultaneous correction of the associated stenosiswith the tip of the endoscope. A visual controlled opening of the stenosis was impossible in 3 cases due to a too narrow presaccal anatomy (n = 1), an osseous duct stenosis (n = 1), and a bulging membrane of Hasner into the inferior nasal meatus (n = 1). Postoperative findings were classified into four categories: poor, fair, good and excellent. Good results were documented in 16.7% (n = 3) and excellent results in 77.7% (n = 14). The bony obstruction was treated with dacryocystorhinostomy. A minimum follow-up of 3 months was considered for final clinical analysis. Ten patients' parents (12 surgeries) were interviewed by telephone (mean follow-up 24.8 months). No recurrence of stenosis and no further postoperative complications were observed.
DE is a diagnostic and therapeutic option for complex CNLDO in patients before the age of 1 year. The outcome of DE in the 3 months follow-up is highly indicative of positive final results in terms of patency of the lacrimal duct.
先天性鼻泪管阻塞(CNLDO)是婴儿期溢泪最常见的原因。大多数病例在1岁时可自行缓解。然而,阻塞对保守治疗或手术治疗的结果有负面影响,尤其是在复杂的CNLDO病例中。当病情持续数月以上时,1岁左右早期进行泪道内窥镜检查(DE)可能会取得良好效果。本研究的目的是分析1岁以内复杂CNLDO早期DE的成功率和有效性。
呈现一项回顾性、非对照病例系列研究。对1至12个月大患有严重复发性急性或慢性泪囊炎的患者在全身麻醉下进行DE。分析其病史、3个月后的术中及术后结果以及通过家长访谈来调查成功率。
共对16例年龄在1至12个月(平均7.3±3.4个月)的患者连续进行了18次DE。9条泪道被诊断为对探通/冲洗治疗无效的持续性慢性泪囊炎。其余9例表现为复发性急性泪囊炎。18例均进行了诊断性DE。15条泪道(83.3%)进行了治疗性DE,同时用内窥镜尖端矫正相关狭窄。3例因泪囊前解剖结构过窄(n = 1)、骨性泪道狭窄(n = 1)和Hasner瓣膨入下鼻道(n = 1)而无法在内窥镜直视下打开狭窄。术后结果分为四类:差、一般、好和优。良好结果记录为16.7%(n = 3),优秀结果为77.7%(n = 14)。骨性阻塞采用泪囊鼻腔吻合术治疗。最终临床分析的最短随访时间为3个月。通过电话采访了10名患者的家长(12次手术)(平均随访24.8个月)。未观察到狭窄复发及术后进一步并发症。
DE是1岁以内复杂CNLDO患者的一种诊断和治疗选择。DE在3个月随访时的结果高度预示着泪道通畅方面最终会取得积极结果。