Kikuchi Mariko, Tanino Hirokazu, Kosaka Yoshimasa, Sengoku Norihiko, Yamashita Keishi, Minatani Naoko, Nishimiya Hiroshi, Waraya Mina, Katoh Hiroshi, Enomoto Takumo, Kajita Sabine, Woodhams Reiko, Watanabe Masahiko
Department of Surgery, Kitasato University School of Medicine, Kanagawa, Japan.
Department of Surgery, Kitasato University School of Medicine, Kanagawa, Japan
Anticancer Res. 2014 Nov;34(11):6749-53.
With the recent rise in mammography (MMG) screenings there has been an increase in the identification of microcalcifications without lump. Therefore, a vacuum-assisted needle biopsy under stereotactic guidance (ST-MTB) is frequently performed for diagnosis. However, ST-MTB is a highly invasive examination. In this study, we investigated the effectiveness of utilizing contrast-enhanced magnetic resonance imaging (MRI) to differentiate between benign and malignant category 3 (C3) calcifications.
One hundred and sixty-eight patients with microcalcifications underwent contrast-enhanced MRI prior to ST-MTB in our hospital. Their MRI scans were reviewed to determine whether the contrast-enhanced MRI findings were consistent. We calculated the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of contrast-enhanced MRI.
No malignancy was not found in the 51 of the 168 cases analyzed by MRI. The calculated sensitivity, specificity, PPV and NPV of contrast-enhanced MRI were 84%, 82%, 58% and 95%, respectively.
Contrast-enhanced MRI for Category 3 calcified lesions would be a useful diagnostic tool for identifying ST-MTB-indicated patients.
随着近期乳腺钼靶（MMG）筛查的增加，无肿块微钙化的检出率有所上升。因此，常采用立体定向引导下真空辅助针吸活检（ST-MTB）进行诊断。然而，ST-MTB是一种侵入性较强的检查。在本研究中，我们探讨了利用对比增强磁共振成像（MRI）区分3类（C3）钙化灶良恶性的有效性。
我院168例有微钙化的患者在ST-MTB前接受了对比增强MRI检查。对他们的MRI扫描结果进行回顾，以确定对比增强MRI表现是否一致。我们计算了对比增强MRI的敏感性、特异性、阳性预测值（PPV）和阴性预测值（NPV）。
MRI分析的168例病例中，51例未发现恶性病变。对比增强MRI计算的敏感性、特异性、PPV和NPV分别为84%、82%、58%和95%。
对于3类钙化病变，对比增强MRI将是识别ST-MTB适应证患者的一种有用的诊断工具。
