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动脉粥样硬化性肾动脉狭窄与血管重建术

Atherosclerotic renal artery stenosis and revascularization.

作者信息

Choi Sharon S

机构信息

Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

出版信息

Expert Rev Cardiovasc Ther. 2014 Dec;12(12):1419-25. doi: 10.1586/14779072.2014.977258. Epub 2014 Nov 5.

Abstract

Atherosclerotic renovascular disease is the most common cause of secondary hypertension. The patients with renovascular disease are at increased risk for adverse cardiac outcomes. Recent trials comparing medical therapy alone to medical therapy with stenting are flawed, but lay to rest any existing debate that unselected revascularization is unwarranted; however, revascularization may be appropriate in high-risk populations. Defining an appropriate population for revascularization is an area of ongoing study. Furthermore, delivery of optimal medical therapy in this population is inadequate. This review describes recent developments in renal artery revascularization.

摘要

动脉粥样硬化性肾血管疾病是继发性高血压最常见的病因。肾血管疾病患者发生不良心脏结局的风险增加。最近比较单纯药物治疗与药物治疗联合支架置入的试验存在缺陷,但平息了关于未经选择的血运重建是否必要的现有争论;然而,血运重建可能适用于高危人群。确定合适的血运重建人群是一个正在进行研究的领域。此外,在这一人群中提供最佳药物治疗并不充分。本综述描述了肾动脉血运重建的最新进展。

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