Kimura Yoshiki, Matsumoto Hiroshi, Oosawa Motoyasu, Fujita Minoru, Tarumi Ken-Ichi, Kamada Tomoari, Shiotani Akiko, Haruma Ken
Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School.
Nihon Shokakibyo Gakkai Zasshi. 2014 Nov;111(11):2121-30.
We evaluated the relationship between colorectal neoplasms and visceral obesity using computed tomographic colonography and adipocytokine levels. We included 123 patients and classified them into four groups as per computed tomographic colonography: no lesion (NL; n=40), adenomatous polyp (polyp; n=41), early colorectal cancer (eCRC; n=21), and advanced CRC (aCRC; n=21). We also measured the patients' serum metabolic markers and adipocytokine levels. The visceral adiposity index in the polyp and eCRC groups was significantly higher than that in the NL group. Visceral obesity is an important risk factor for the development of colonic polyps. Computed tomographic colonography could be a useful examination technique not only for diagnosis of colorectal neoplasms but also for simultaneous evaluation of visceral obesity.
我们使用计算机断层结肠成像和脂肪细胞因子水平评估了结直肠肿瘤与内脏肥胖之间的关系。我们纳入了123名患者,并根据计算机断层结肠成像将他们分为四组:无病变(NL;n = 40)、腺瘤性息肉(息肉;n = 41)、早期结直肠癌(eCRC;n = 21)和晚期结直肠癌(aCRC;n = 21)。我们还测量了患者的血清代谢标志物和脂肪细胞因子水平。息肉组和eCRC组的内脏肥胖指数显著高于NL组。内脏肥胖是结肠息肉发生的重要危险因素。计算机断层结肠成像可能是一种有用的检查技术,不仅可用于诊断结直肠肿瘤,还可同时评估内脏肥胖。