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[一例胰腺浸润性微乳头状癌合并导管内乳头状黏液性肿瘤]

[A case of invasive micropapillary carcinoma of the pancreas concomitant with intraductal papillary mucinous neoplasm].

作者信息

Tanaka Hiroki, Baba Youichirou, Matsusaki Shimpei, Isono Yoshiaki, Sase Tomohiro, Okano Hiroshi, Saito Tomonori, Mukai Katsumi, Kaneko Hiroshi, Watanabe Gen

机构信息

Department of Gastroenterology, JA Suzuka General Hospital.

出版信息

Nihon Shokakibyo Gakkai Zasshi. 2014 Nov;111(11):2149-56.

Abstract

Invasive micropapillary carcinoma (IMPC), a rare subtype of adenocarcinoma, has a high incidence of lymph node metastasis and is associated with a poor prognosis. A 77-year-old woman was admitted to our hospital for the assessment of intraductal papillary mucinous neoplasm (IPMN). We diagnosed her with pancreatic cancer concomitant with IPMN and performed pancreaticoduodenectomy. The lesion was predominantly composed of ductal adenocarcinoma with a micropapillary component. On immunohistochemical analysis, a characteristic " inside-out pattern" was observed in the micropapillary component. This confirmed the diagnosis of pancreatic cancer with a micropapillary component. In the present report, we describe a very rare case of IMPC of the pancreas.

摘要

浸润性微乳头状癌(IMPC)是腺癌的一种罕见亚型,淋巴结转移发生率高且预后较差。一名77岁女性因导管内乳头状黏液性肿瘤(IPMN)入院接受评估。我们诊断她患有胰腺癌合并IPMN,并进行了胰十二指肠切除术。病变主要由伴有微乳头成分的导管腺癌组成。免疫组化分析显示,微乳头成分呈现出特征性的“由内向外模式”。这证实了伴有微乳头成分的胰腺癌的诊断。在本报告中,我们描述了一例非常罕见的胰腺IMPC病例。

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