Ergul Z, Akinci M, Kulacoglu H
Chirurgia (Bucur). 2014 Sep-Oct;109(5):613-9.
To identify rates of recurrence and hypothyroidism after hemithyroidectomy for unilateral nodular thyroid diseases and its advantages over bilateral radical resections.
Fifty patients who underwent thyroid lobectomy with unilateral thyroid disease were included. Follow-up with thyroid function tests on the first month and then once every three months, as well as ultrasonography controls once a year were performed postoperatively. Recurrence, which was accepted asat least one nodule with a diameter of 5 mm on the remnant lobe, and the need for postoperative thyroxin therapy were analysed, along with the relation of both with preoperative medical therapy, histological results, numbers and diameters of thyroid nodules, follow-up duration.
The incidence of recurrent disease after hemithyroidectomy was 12% after a mean follow-up time of 25.2 months (range, 10-43) while the incidence of clinical hypothyroidism which needs thyroxin therapy was 8%. Gender, age,substitutive and suppressive therapy before operation,histological evaluation, the presence of multiple nodules and diameter of nodules were predictive of neither recurrence nor post operative thyroxin therapy.
Hemithyroidectomy for unilateral thyroid disease has a moderate rate of recurrence, low rates of hypothyroidism and rare postoperative complications, with short hospital stay.
确定单侧结节性甲状腺疾病行甲状腺半叶切除术后的复发率和甲状腺功能减退症发生率,以及其相对于双侧根治性切除术的优势。
纳入50例行单侧甲状腺疾病甲状腺叶切除术的患者。术后第一个月进行甲状腺功能检查,之后每三个月检查一次,每年进行一次超声检查。分析复发情况(定义为残余叶至少有一个直径5 mm的结节)、术后甲状腺素治疗需求,以及二者与术前药物治疗、组织学结果、甲状腺结节数量和直径、随访时间的关系。
平均随访25.2个月(范围10 - 43个月)后,甲状腺半叶切除术后复发疾病的发生率为12%,而需要甲状腺素治疗的临床甲状腺功能减退症的发生率为8%。性别、年龄、术前替代和抑制治疗、组织学评估、多发结节的存在及结节直径均不能预测复发或术后甲状腺素治疗。
单侧甲状腺疾病行甲状腺半叶切除术复发率中等,甲状腺功能减退症发生率低,术后并发症罕见,住院时间短。