Friedman A J
Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Fertil Steril. 1989 Mar;51(3):526-8. doi: 10.1016/s0015-0282(16)60568-x.
Five premenopausal women with leiomyomata uteri were treated with leuprolide for 3 months and demonstrated a reduction in mean uterine volume of 49%. Cyclic conjugated equine estrogens and MPA were added to leuprolide therapy during the ensuing 24 months, with no significant changes in mean uterine volume or peripheral bone density.