Shi Shuang, Fang Qi-Gen, Sun Changfu
From the *Department of Pediatric Dentistry, and †Department of Oromaxillofacial-Head and Neck Surgery and Department of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University, Shenyang, Liaoning, PR China.
J Craniofac Surg. 2014 Nov;25(6):e598-9. doi: 10.1097/SCS.0000000000000764.
We reported 1 case of salivary duct carcinoma (SDC) in the mandible. The patient complained of pain and a growing mass in the right submandibular area for approximately 2 months. On clinical examination, there was a mass under the right angle of the mandible with a size of approximately 3 × 3 cm, a smooth surface, a poor activity, and a hard texture. Panoramic radiograph revealed poorly circumscribed area. Computed tomography presented mandible central destruction. Biopsy examination showed a malignant tumor that originated in the central epithelium of the mandible. An operation of unilateral selective neck dissection and mandible subtotal ectomy was performed. Postoperative pathology reported SDC. The patient received postoperative radiation and stayed alive at last follow-up without disease recurrence. Ablative resection and postoperative radiotherapy were the standard treatment stratagem for SDC, but trastuzumab therapy might play a key role in treating the disease in future.
我们报告了1例下颌骨涎腺导管癌（SDC）。患者主诉右侧下颌下区疼痛并肿物增大约2个月。临床检查发现，在下颌骨右角下方有一肿物，大小约为3×3 cm，表面光滑，活动度差，质地硬。全景X线片显示边界不清的区域。计算机断层扫描显示下颌骨中央破坏。活检检查显示为起源于下颌骨中央上皮的恶性肿瘤。行单侧选择性颈清扫术及下颌骨次全切除术。术后病理报告为SDC。患者接受了术后放疗，在最后一次随访时存活且无疾病复发。手术切除及术后放疗是SDC的标准治疗策略，但曲妥珠单抗治疗未来可能在该病治疗中发挥关键作用。
