Cornelius Jack R, Haas Gretchen L, Appelt Cathleen J, Walker Jon D, Fox Lauren J, Kasckow John W, Luther James F, Salloum Ihsan M
VISN 4 Mental Illness Research, Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System.
Int J Med Biol Front. 2012;18(11):783-794.
This manuscript begins by reviewing the literature concerning the use of the SCID versus the PCL for diagnosing PTSD, and by reviewing the literature regarding the presence of suicidal ideation as a clinical correlate of PTSD. This manuscript then describes our recent study involving PTSD among Veterans, which assessed the presence of suicidal ideation as a clinical correlate of PTSD, as diagnosed by the SCID versus as diagnosed by the PCL. We hypothesized that the presence of suicidal ideation would be associated with a diagnosis of PTSD. Subjects were 101 Veterans recruited from VA behavioral health and substance use treatment clinics in the VA Pittsburgh Healthcare System. The study compared correlations of suicidal ideation with PTSD as determined with the PTSD Checklist versus the Structured Clinical Interview for DSM-IV, and utilized question 9 of the Beck Depression Inventory for assessing presence of SI. PTSD was diagnosed in 15 subjects using the SCID, and in 15 subjects using the PTSD Checklist. SI were reported by 16 subjects. The presence of SI was significantly associated with the diagnosis of PTSD on the PCL (chi-square=5.73, df=1, p=0.017) but not on the SCID (chi-square=0.08, df=1, p=0.773). These findings suggest that SI associated with the diagnosis of PTSD among Veterans are better ascertained by the PCL as compared to the more elaborate diagnostic algorithm used in the SCID. The current study finding raises the possibility that a less complicated diagnostic assessment instrument such as the PCL may be superior to the SCID, a more complicated instrument for diagnosing PTSD, at least in some populations.
本手稿首先回顾了关于使用《精神障碍诊断与统计手册》第四版临床定式检查(SCID)与创伤后应激障碍检查表(PCL)来诊断创伤后应激障碍(PTSD)的文献,以及关于自杀意念作为PTSD临床相关因素存在情况的文献。然后,本手稿描述了我们最近一项针对退伍军人中PTSD的研究,该研究评估了自杀意念作为PTSD临床相关因素的存在情况,PTSD分别由SCID和PCL进行诊断。我们假设自杀意念的存在与PTSD的诊断相关。研究对象为从匹兹堡退伍军人医疗系统的退伍军人事务部行为健康和物质使用治疗诊所招募的101名退伍军人。该研究比较了用PTSD检查表与《精神障碍诊断与统计手册》第四版结构化临床访谈确定的自杀意念与PTSD之间的相关性,并使用贝克抑郁量表的问题9来评估自杀意念的存在情况。使用SCID诊断出15名PTSD患者,使用PTSD检查表诊断出15名PTSD患者。16名受试者报告有自杀意念。在PCL上,自杀意念的存在与PTSD的诊断显著相关(卡方=5.73,自由度=1,p=0.017),但在SCID上则不然(卡方=0.08,自由度=1,p=0.773)。这些发现表明,与SCID中使用的更精细的诊断算法相比,PCL能更好地确定退伍军人中与PTSD诊断相关的自杀意念。当前的研究结果提出了一种可能性,即至少在某些人群中,像PCL这样不太复杂的诊断评估工具可能优于用于诊断PTSD的更复杂的工具SCID。