Mid-Atlantic Mental Illness Research, Education and Clinical Center, VA Medical Center, 508 Fulton Street, Durham, NC 27705, United States.
J Anxiety Disord. 2011 Jan;25(1):12-8. doi: 10.1016/j.janxdis.2010.06.025. Epub 2010 Jul 7.
This study examined the relation between posttraumatic stress disorder (PTSD) and suicidal ideation among U.S. military veterans deployed during Operation Enduring Freedom and/or Operation Iraqi Freedom. Specific aims included investigation of (1) whether PTSD was associated with suicidal ideation after controlling for combat exposure and history of suicide attempt(s), (2) whether PTSD was associated with suicidal ideation absent a co-occurring depressive disorder (MDD) or alcohol use disorder (AUD), (3) whether co-occurring MDD or AUD increased risk of suicidal ideation among those with PTSD and (4) whether PTSD/MDD symptom clusters were differentially associated with suicidal ideation. Results pointed to unique effects associated with prior suicide attempt(s), PTSD and MDD. PTSD-diagnosed participants with co-occurring MDD or AUD were not significantly more likely to endorse suicidal ideation than PTSD-diagnosed participants without such comorbidity. The 'emotional numbing' cluster of PTSD symptoms and the 'cognitive-affective' cluster of MDD symptoms were uniquely associated with suicidal ideation.
这项研究考察了创伤后应激障碍(PTSD)与在持久自由行动和/或伊拉克自由行动中部署的美国退伍军人自杀意念之间的关系。具体目标包括调查:(1)在控制战斗暴露和自杀企图史后,PTSD 是否与自杀意念有关;(2)是否存在共病性重性抑郁障碍(MDD)或酒精使用障碍(AUD)时,PTSD 与自杀意念有关;(3)在 PTSD 患者中,共病 MDD 或 AUD 是否会增加自杀意念的风险;(4)PTSD/MDD 症状群是否与自杀意念有不同的关联。结果表明,先前的自杀企图、PTSD 和 MDD 与独特的影响有关。共病 MDD 或 AUD 的 PTSD 诊断参与者与没有这种共病的 PTSD 诊断参与者相比,并不更有可能表示有自杀意念。PTSD 症状的“情感麻木”集群和 MDD 症状的“认知-情感”集群与自杀意念有独特的关联。