Sato Takaki, Mimura Masashi, Sugiyama Tetsuya, Maeno Takatoshi, Ishizaki Eisuke, Minami Masahiro, Sugasawa Jun, Ikeda Tsunehiko
From the Department of Ophthalmology, Osaka Medical College, Osaka, Japan.
Retin Cases Brief Rep. 2007 Summer;1(3):172-4. doi: 10.1097/01.ICB.0000279653.16358.ce.
Senior-Loken syndrome is a rare disorder that combines juvenile nephronophthisis with retinitis pigmentosa.
Case report.
A 9-year-old Japanese girl diagnosed with Senior-Loken syndrome subsequently developed severe Coats disease-like exudative retinopathy. Although retinal coagulation, pars plana lensectomy, and vitrectomy were performed, she lost light perception in both eyes.
Faulty vascular morphogenesis and its dysfunction might contribute to the development of Coats disease-like exudative retinopathy in Senior-Loken syndrome.
Senior-Loken综合征是一种罕见的疾病，它将青少年肾单位肾痨与色素性视网膜炎结合在一起。
病例报告。
一名9岁日本女孩被诊断为Senior-Loken综合征，随后发展为严重的类Coats病渗出性视网膜病变。尽管进行了视网膜凝固、睫状体平坦部晶状体切除术和玻璃体切除术，但她双眼失去了光感。
血管形态发生缺陷及其功能障碍可能导致Senior-Loken综合征中类Coats病渗出性视网膜病变的发生。
