Fsadni Peter, Fsadni Claudia, Caruana Montaldo Brendan
Department of Medicine, Mater Dei Hospital, Msida MSD 2090, Malta.
Ear Nose Throat J. 2014 Oct-Nov;93(10-11):E15-7.
Tuberculosis (TB) of the larynx is usually associated with concomitant pulmonary TB, but approximately 20% of cases represent primary disease. We report the case of an 85-year-old woman with asthma who presented with a 6-month history of persistent hoarseness. Bronchoscopy confirmed the presence of a lesion in the hemilarynx, and histology identified tuberculoid granulomas that were suggestive of TB. Treatment with a combination of isoniazid, rifampicin, pyrazinamide, and ethambutol led to a complete resolution of symptoms. A high index of suspicion for laryngeal TB is required in patients who present with hoarseness.
喉结核通常与合并的肺结核相关，但约20%的病例为原发性疾病。我们报告一例85岁哮喘女性病例，该患者有6个月持续性声音嘶哑病史。支气管镜检查证实半喉存在病变，组织学检查发现结核样肉芽肿，提示为结核病。异烟肼、利福平、吡嗪酰胺和乙胺丁醇联合治疗使症状完全缓解。对出现声音嘶哑的患者，需要高度怀疑喉结核。
