Tagami Takashi, Matsui Hiroki, Horiguchi Hiromasa, Fushimi Kiyohide, Yasunaga Hideo
Department of Clinical Epidemiology and Health Economics, School of Public Health, Graduate School of Medicine, The University of Tokyo, Tokyo; Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo.
Circ J. 2015;79(1):55-60. doi: 10.1253/circj.CJ-14-0916. Epub 2014 Nov 17.
The epidemiology of traumatic thoracic aortic injury has not been reported in many countries, so we investigated the current trends in Japan.
Patients with traumatic thoracic aortic injury from July 2007 to March 2013 were identified using a Japanese nationwide administrative database, the Diagnosis Procedure Combination inpatient database. The trends in crude in-hospital mortality and proportion of endovascular repair use among patients with repair were evaluated over time. A total of 617 incident cases of thoracic aortic injury were identified at 234 hospitals, and categorized into endovascular repair (n=126), open repair (n=76), and non-repair (n=415) groups. The in-hospital mortality rate for each of these groups was 5.6%, 15.8%, and 45.3%, respectively. The in-hospital survival rate was higher in the endovascular repair group than in the open repair group (log-rank χ(2)=4.9; P=0.03). Although the crude in-hospital mortality did not change significantly during the study period (Mantel-Haenszel trend test, P=0.10), the proportion of endovascular repair use among all repair cases increased significantly (P<0.001).
The results of the present nationwide study suggest that the endovascular approach to treatment of thoracic aortic injury in Japan gained in popularity from 2007 to 2012.
许多国家尚未报道创伤性胸主动脉损伤的流行病学情况,因此我们对日本当前的趋势进行了调查。
利用日本全国性行政数据库——诊断程序组合住院患者数据库,确定了2007年7月至2013年3月期间患有创伤性胸主动脉损伤的患者。评估了住院期间粗死亡率和接受修复患者中血管内修复使用比例随时间的变化趋势。在234家医院共确定了617例胸主动脉损伤的新发病例,并分为血管内修复组(n = 126)、开放修复组(n = 76)和未修复组(n = 415)。这些组的住院死亡率分别为5.6%、15.8%和45.3%。血管内修复组的住院生存率高于开放修复组(对数秩χ(2)=4.9;P = 0.03)。尽管在研究期间粗住院死亡率没有显著变化(Mantel-Haenszel趋势检验,P = 0.10),但所有修复病例中血管内修复的使用比例显著增加(P < 0.001)。
本全国性研究结果表明,2007年至2012年期间,日本采用血管内方法治疗胸主动脉损伤的情况越来越普遍。