Buznikov G A, Shmukler Iu B
Ontogenez. 1978;9(2):173-8.
The dated treatment of the early embryos of an irregular (flat) sea urchin Scaphechinus mirabilis by neuropharmacological drugs (anti-neurotransmitters) during one of the first four cleavage divisions results in the impairment of intercellular connections and leads to the formation of twin embryos, dwarf embryos, embryos of the dumb-bell shape etc. In the experiments with some of the drugs under study such developmental abnormalities were not seen or were expressed much more weakly when serotonin or bufotenin (N,N-dimethylserotonin) were added to the medium. A suggestion is put forward that the early embryos possess an intracellular mechanism participating in the interaction between the cells and operating via endogenous monoamines, primarily serotonin.
在用神经药理学药物（抗神经递质）对不规则（扁平）海胆奇异刻肋海胆的早期胚胎进行处理时，在最初四次卵裂分裂中的某一次进行处理，会导致细胞间连接受损，并导致双胚胎、矮小胚胎、哑铃状胚胎等的形成。在对一些所研究药物进行的实验中，当向培养基中添加血清素或蟾蜍色胺（N,N-二甲基血清素）时，未观察到这种发育异常，或者这种异常表现得要弱得多。有人提出，早期胚胎拥有一种细胞内机制，该机制参与细胞间相互作用，并通过内源性单胺（主要是血清素）发挥作用。
