Rapoport Zh Zh, Shestovitskiĭ V A, Liubchenko O F
Gig Tr Prof Zabol. 1989(1):8-11.
In order to raise efficacy of primary prevention of platinosis an obsidan-based test (40 mg for internal use) was also used in vocational selection. After the obsidan-based test the decrease of pneumotachometric indicators was noted that reflected deficiency of the functional state of bronchial beta-adrenoreceptors by 6% and higher and was regarded as unfavourable. Of 110 examined persons 16 (14.5%) had significant test results. Similar deficiency was detected in 27 workers with respiratory platinosis, that fact verified the significance of beta-AR deficiency in the disease pathogenesis. The possibility of raising efficacy of primary prevention of respiratory platinosis was stressed due to the use of the additional obsidan-based test.
为提高铂中毒一级预防的效果，在职业选拔中还使用了基于黑曜石的检测方法（内服40毫克）。在基于黑曜石的检测后，发现呼吸速度测量指标下降，这反映出支气管β-肾上腺素能受体功能状态不足6%及以上，被视为不利情况。在110名受检者中，有16人（14.5%）检测结果显著。在27名患有呼吸道铂中毒的工人中也检测到了类似的不足，这一事实证实了β-肾上腺素能受体不足在该疾病发病机制中的重要性。强调了使用额外的基于黑曜石的检测方法提高呼吸道铂中毒一级预防效果的可能性。
