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大鼠在操作性进食任务学习过程中的行为参数研究以及食用植物蜕皮甾酮提取物后的生化指标评估。

Study of behavioral parameters during learning of rats in an operant feeding task and evaluation of biochemical indexes after dietary consumption of the phytoecdysteroid extract.

作者信息

Murtazina E P, Sidorova Yu S, Zhuravlev B V, Mazo V K, Zorin S N, Volodin V V

机构信息

P. K. Anokhin Research Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia,

出版信息

Bull Exp Biol Med. 2014 Nov;158(1):4-8. doi: 10.1007/s10517-014-2678-7. Epub 2014 Nov 19.

DOI:10.1007/s10517-014-2678-7
PMID:25403385
Abstract

Experiments on rats were performed to study the process of operant feeding learning, locomotor activity, oxygen consumption, and concentrations of corticosterone, β-endorphin, and prostaglandin E in blood serum after dietary treatment with the phytoecdysteroid extract. Administration of phytoecdysteroids was followed by the improvement of learning and increase in oxygen consumption and locomotor activity. Locomotor activity and oxygen consumption in the majority of control rats and phytoecdysteroid-treated animals were shown to be interrelated with the total locomotor activity and goal-directed operant behavior, respectively. No significant differences were found in the concentration of hormones in blood serum from animals of the control and treatment groups.

摘要

对大鼠进行实验,以研究经植物蜕皮甾酮提取物饮食处理后操作性进食学习过程、运动活动、耗氧量以及血清中皮质酮、β-内啡肽和前列腺素E的浓度。给予植物蜕皮甾酮后,学习能力得到改善,耗氧量和运动活动增加。结果显示,大多数对照大鼠和经植物蜕皮甾酮处理动物的运动活动和耗氧量分别与总运动活动和目标导向的操作性行为相关。对照组和处理组动物血清中的激素浓度未发现显著差异。

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