Järvinen M, Jozsa L, Hurme M, Einola S
Department of Surgery, University Central Hospital of Tampere, Finland.
Acta Histochem. 1989;85(1):9-14. doi: 10.1016/S0065-1281(89)80089-3.
The activity and distribution of 10 enzymes was determined in the ruptured knee meniscus of 23 patients, when meniscus was operatively removed. The activities of NADH and SDH indicating oxydative energy metabolism were low in the ruptured meniscus as well as in the synovium close to it. On the contrary, NADPH and LDH, indicating anaerobic energy metabolism and G-6-PDH as an indicator of pentose-phosphate shunt, showed moderate or high activity. The activities of GLDH, ATPase, AcPase, AlPase, and LAPase were low in the meniscus tissue, but moderate and sometimes high in synovial tissue and fibroblasts close to the meniscus. In the vascular walls these enzyme activities all were moderate or high indicating reparative capacity in the peripheral, vascularized part of meniscus. The age of the patients as well as the time interval between the trauma and the operation was not in relationship with enzyme activities studied.
对23例接受半月板手术切除的患者破裂膝关节半月板中的10种酶的活性和分布进行了测定。表明氧化能量代谢的NADH和SDH的活性在破裂半月板及其附近的滑膜中均较低。相反，表明无氧能量代谢的NADPH和LDH以及作为磷酸戊糖分流指标的G-6-PDH显示出中等或高活性。GLDH、ATPase、AcPase、AlPase和LAPase的活性在半月板组织中较低，但在滑膜组织和半月板附近的成纤维细胞中为中等，有时较高。在血管壁中，这些酶的活性均为中等或高，表明半月板外周血管化部分具有修复能力。患者的年龄以及创伤与手术之间的时间间隔与所研究的酶活性无关。
