Ma Hong-Wei, Nie Tie-Jian, Ma Yong-Tao, Wu Ya-Qiong, Jia Zhan-Sheng, Bai Xue-Fan
Center of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2014 Nov;16(11):1091-5.
To study the clinical characteristics of pediatric hemorrhagic fever with renal syndrome (HFRS), and to improve its understanding so as to reduce the misdiagnosis.
A retrospective analysis was performed on the clinical data of 26 children with HFRS between January 2009 and December 2012.
The age of disease onset was mainly distributed between 7 and 14 years (23 cases, 88%), and the male-to-female ratio was 1.89:l. The clinical manifestations of pediatric HFRS varied. The early symptoms resembled those of a cold, and in the course of HFRS, most patients developed digestive symptoms such as vomiting and abdominal pain. The laboratory examinations usually implicated platelet changes, and the imaging examinations revealed polyserous effusions. The prominent complication was myocardial injury.
Pediatric HFRS mainly occurs in school-age children, more commonly in males. HFRS does not have typical clinical manifestations or symptoms, so it should be distinguished from cold or appendicitis at the early stage. When applying the fluid replacement therapy, the cardiac function should be carefully monitored in case of heart failure.
研究儿童肾综合征出血热（HFRS）的临床特征，提高对其的认识以减少误诊。
对2009年1月至2012年12月期间26例儿童HFRS患者的临床资料进行回顾性分析。
发病年龄主要分布在7至14岁（23例，88%），男女比例为1.89∶1。儿童HFRS的临床表现多样。早期症状类似感冒，在HFRS病程中，多数患者出现呕吐、腹痛等消化道症状。实验室检查常提示血小板变化，影像学检查显示多浆膜腔积液。突出的并发症是心肌损伤。
儿童HFRS主要发生于学龄儿童，男性更为常见。HFRS没有典型的临床表现或症状，因此在早期应与感冒或阑尾炎相鉴别。在应用补液疗法时，应仔细监测心功能以防发生心力衰竭。
