Lantz Andrea G, O'Malley Padraic, Ordon Michael, Lee Jason Y
Department of Urology, Dalhousie University, Halifax, NS;
Division of Urology, Department of Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON.
Can Urol Assoc J. 2014 Sep;8(9-10):347-51. doi: 10.5489/cuaj.2037.
Percutaneous nephrolithotomy (PCNL) may be associated with significant ionizing radiation exposure for patients and operating room staff. Endoscopic-guided PCNL (ePCNL) is a technique that may be associated with less radiation exposure. This study examines ePCNL-related radiation exposure (fluoroscopy time, effective dose) and investigates variables that may predict increased exposure.
A retrospective review of all consecutive ePCNLs performed at our institution, by a single surgeon, was conducted between November 2011 and November 2013. Patient demographics, stone characteristics and perioperative details were recorded, including radiation exposure. Pearson and Spearman correlation were used to assess variables correlated with radiation exposure.
In total, 55 ePCNL cases were included in the study. The mean age was 60 ± 15 years, mean body mass index (BMI) 30.0 ± 6.4 kg/m(2) and mean stone size 3.2 × 2.1 cm. Seven cases (13%) involved complete staghorn stones, and 69% involved supracostal punctures. The mean fluoroscopy time was 3.4 ± 2.3 minutes, mean ED 2.4 ± 1.9 mSv. The treatment success rate, assessed 1-week postoperatively, was 87.3% and 7.3% of cases required ancillary procedures. The overall complication rate was 29%, but only 3 cases (5.5%) were Clavien ≥3. Longer fluoroscopy time correlated with increased stone size (p < 0.01), longer operative time (p < 0.01) and lower treatment success rates (p < 0.01); higher effective dose correlated with longer fluoroscopy time (p < 0.01) and increased skin-to-stone distance (p < 0.01). BMI did not correlate with fluoroscopy time or effective dose.
Outcomes of ePCNL are comparable to traditional PCNL techniques and may be associated with lower radiation exposure, particularly beneficial for patients with higher BMI.
经皮肾镜取石术(PCNL)可能会使患者和手术室工作人员受到大量电离辐射。内镜引导下经皮肾镜取石术(ePCNL)是一种可能与较少辐射暴露相关的技术。本研究探讨了与ePCNL相关的辐射暴露(透视时间、有效剂量),并调查了可能预示暴露增加的变量。
对2011年11月至2013年11月间在我们机构由一名外科医生连续进行的所有ePCNL手术进行回顾性研究。记录患者人口统计学资料、结石特征和围手术期细节,包括辐射暴露情况。采用Pearson和Spearman相关性分析来评估与辐射暴露相关的变量。
本研究共纳入55例ePCNL病例。平均年龄为60±15岁,平均体重指数(BMI)为30.0±6.4kg/m²,平均结石大小为3.2×2.1cm。7例(13%)为完全鹿角形结石,69%的病例采用肋上穿刺。平均透视时间为3.4±2.3分钟,平均有效剂量为2.4±1.9mSv。术后1周评估的治疗成功率为87.3%,7.3%的病例需要辅助手术。总体并发症发生率为29%,但只有3例(5.5%)为Clavien≥3级。透视时间越长,与结石尺寸增大(p<0.01)、手术时间延长(p<0.01)和治疗成功率降低(p<0.01)相关;有效剂量越高,与透视时间延长(p<0.01)和皮肤至结石距离增加(p<0.01)相关。BMI与透视时间或有效剂量无关。
ePCNL的治疗效果与传统PCNL技术相当,且可能与较低的辐射暴露相关,这对BMI较高的患者尤其有益。