Shank Erik S, Martyn Jeevendra A, Donelan Mathias B, Perrone Anthony, Firth Paul G, Driscoll Daniel N
From the *Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston; and †Department of Surgery, Shriners Hospital for Children®, Harvard Medical School, Boston.
J Burn Care Res. 2016 May-Jun;37(3):e213-7. doi: 10.1097/BCR.0000000000000174.
Pediatric patients face multiple reconstructive surgeries to reestablish function and aesthetics postburn injury. Often, the site of the harvested graft for these reconstructions is reported to be the most painful part of the procedure and a common reason for deferring these reconstructive procedures. This study in pediatric burn patients undergoing reconstructive procedures examined the analgesia response to local anesthetic infiltration versus either a single ultrasound-guided regional nerve block of the lateral femoral cutaneous nerve (LFCN) or a fascia iliaca compartment block with catheter placement and continuous infusion. Nineteen patients were randomized to one of three groups (infiltration, single-shot nerve block, or compartment block with catheter) and received intraoperative analgesia intervention. Postoperatively, visual analog scale pain scores were recorded-for pain at the donor site-every 4 hours while awake-for 48 hours. This nonparametric data was analyzed using a two-way ANOVA, Friedman's test, and Kruskal-Wallis test, with significance determined at P < 0.05. The analysis demonstrated that the patients in the regional anesthesia groups were significantly more comfortable over the 48 hour hospital course than the patients in the control group. The patients receiving a single-shot block of the LFCN were more comfortable on postoperative day (POD) 0 while the catheter patients were more comfortable on POD 1 and POD 2. There was not a statistically significant difference in opioid requirements in any group. Regional anesthetic block of the LFCN, with or without catheter placement, provides an improved postoperative experience for the pediatric patient undergoing reconstructive surgery with lateral/anterolateral skin graft versus local anesthesia infiltration of donor site. For optimal comfort throughout the postoperative period, an ultrasound-guided block with continuous catheter may be beneficial.
小儿烧伤患者在烧伤后需要进行多次重建手术以恢复功能和美观。通常,这些重建手术中取皮部位被认为是手术过程中最疼痛的部分,也是推迟这些重建手术的常见原因。本研究对接受重建手术的小儿烧伤患者进行了观察,比较了局部麻醉药浸润与单次超声引导下股外侧皮神经(LFCN)区域神经阻滞或置管并持续输注的髂筋膜间隙阻滞的镇痛效果。19例患者被随机分为三组(浸润组、单次神经阻滞组或置管间隙阻滞组),并接受术中镇痛干预。术后,在患者清醒的48小时内,每4小时记录一次供皮区疼痛的视觉模拟评分。使用双向方差分析、Friedman检验和Kruskal-Wallis检验对这些非参数数据进行分析,P<0.05为差异有统计学意义。分析表明,在48小时的住院过程中,区域麻醉组患者比对照组患者明显更舒适。接受LFCN单次阻滞的患者在术后第0天更舒适,而置管患者在术后第1天和第2天更舒适。各组间阿片类药物需求量无统计学显著差异。对于接受外侧/前外侧皮肤移植重建手术的小儿患者,LFCN区域麻醉阻滞(无论是否置管)比供皮区局部麻醉浸润能提供更好的术后体验。为了在术后整个期间获得最佳舒适度,超声引导下连续置管阻滞可能有益。