Gunasekera Nicole, Murphy George F, Sheth Vaneeta M
Harvard Medical School, Boston, Mass., USA.
Dermatology. 2015;230(1):11-5. doi: 10.1159/000366197. Epub 2014 Nov 18.
Inflammatory vitiligo with raised borders (IVRB) is a rare subtype of vitiligo described as having a rim of raised erythema at the periphery of the depigmented patches. The etiology is poorly understood, and there are few reports of successful treatment of the condition in the literature. We report a 38-year-old South Asian male who presented with diffuse depigmented macules and patches surrounded by blue-gray rims involving a large body surface area. Light microscopy revealed inflammatory vitiligo. He was treated with 2 courses of oral prednisone and whole-body narrow-band ultraviolet B (NB-UVB) therapy, which resulted in cessation of disease spread as well as substantial repigmentation. Our observation suggests that early and aggressive treatment can lead to significant and rapid improvement in patients with IVRB.
边缘隆起的炎症性白癜风（IVRB）是白癜风的一种罕见亚型，其特征为色素脱失斑周边有一圈隆起的红斑。该病病因尚不清楚，文献中关于成功治疗该病的报道很少。我们报告了一名38岁的南亚男性，他出现了弥漫性色素脱失斑和斑块，周围有蓝灰色边缘，累及大面积体表。光学显微镜检查显示为炎症性白癜风。他接受了2个疗程的口服泼尼松和全身窄谱中波紫外线（NB-UVB）治疗，疾病扩散停止，色素明显恢复。我们的观察表明，早期积极治疗可使IVRB患者显著快速改善。
