de Barros e Silva Pedro G M, Aquino Thiago, Resende Marcos V, Richter Ivo, Barros Cecilia M, Andrioli Vanessa G, Baruzzi Antonio C, Medeiros Caio C J, Furlan Valter
Department of Clinical Research, Hospital Totalcor, Sao Paulo, Brazil.
Am J Case Rep. 2014 Nov 21;15:508-13. doi: 10.12659/AJCR.891301.
Acute aortic syndrome is the modern term that includes aortic dissection, intramural hematoma, and symptomatic aortic ulcer. Iatrogenic coronary artery dissection extending to the aorta during percutaneous coronary intervention is a very rare but life-threatening complication. Despite some reports of spontaneous recovery, most of these patients are treated surgically as a spontaneous aortic dissection, especially if there is a complication of the aortic lesion.
A 52-year-old white female was submitted to an angioplasty in the right coronary without success and the procedure was complicated by a dissection in aortic root with progressive extension to the ascending aorta. This lesion deformed the aortic valve, leaving it with an acute moderate regurgitation. Because of current use of clopidogrel and clinical stability of the patient, the local Heart Team decided to withdrawn this antiplatelet for 5 days before surgery despite the risk related to the aortic syndrome. A new echocardiogram 3 days later showed that the hematoma was reabsorbed with improvement of the aortic insufficiency. An angiotomography confirmed the reabsorption of the hematoma. The surgery was canceled and the patient was maintained in a conservative treatment and discharged. Seventeen months later, she was re-evaluated and was still asymptomatic without aortic regurgitation in the echocardiogram and showing progressive regression of the aortic hematoma in the tomography.
Despite the conservative treatment, this case of iatrogenic aortic dissection complicated by an acute aortic regurgitation had a good evolution in a follow-up of 17 months.
急性主动脉综合征是一个现代术语,包括主动脉夹层、壁内血肿和有症状的主动脉溃疡。经皮冠状动脉介入治疗期间发生的医源性冠状动脉夹层延伸至主动脉是一种非常罕见但危及生命的并发症。尽管有一些自发恢复的报道,但这些患者中的大多数都作为自发性主动脉夹层接受手术治疗,尤其是在存在主动脉病变并发症的情况下。
一名52岁的白人女性接受了右冠状动脉血管成形术,但未成功,该手术并发主动脉根部夹层,并逐渐延伸至升主动脉。该病变使主动脉瓣变形,导致急性中度反流。由于患者目前正在使用氯吡格雷且临床状况稳定,当地心脏团队决定在手术前停用这种抗血小板药物5天,尽管存在与主动脉综合征相关的风险。3天后的一次新的超声心动图显示血肿被重新吸收,主动脉瓣关闭不全有所改善。血管造影证实了血肿的重新吸收。手术被取消,患者接受保守治疗并出院。17个月后,她接受了重新评估,仍然没有症状,超声心动图显示没有主动脉反流,断层扫描显示主动脉血肿逐渐消退。
尽管采用了保守治疗,但这例并发急性主动脉反流的医源性主动脉夹层病例在17个月的随访中病情发展良好。