Huang Chun-Jui, Kwok Chin-Fai, Chou Chung-Hsing, Chou Yu-Ching, Ho Low-Tone, Shih Kuang-Chung
From the *Division of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital; †Department of Medicine, National Yang-Ming University; ‡Department of Neurology, Tri-Service General Hospital; §School of Public Health, National Defense Medical Center; ∥Department of Medical Research, Taipei Veterans General Hospital; and ¶Division of Endocrinology and Metabolism, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
J Investig Med. 2015 Jan;63(1):29-34. doi: 10.1097/JIM.0000000000000120.
Physical activity improves body composition and inflammatory markers in obese individuals, but little is known about the nonobese population.
The aim of this study was to investigate associations between exercise and inflammatory cytokines in lean male adolescents in Taiwan.
This interventional study enrolled a total of 79 normal body weight male adolescents [mean age, 16.8 (1.0) years] from the Army Academy of Taiwan. Body composition and inflammatory markers were measured at baseline and upon completion of a 12-week exercise intervention program.
Subjects' postintervention anthropometric measures, including waist circumference [74.6 (5.2)→72.6 (5.2) cm], hip circumference [92.3 (4.1)→89.9 (5.0) cm], body fat mass [10.2 (3.2)→8.2 (3.2) kg], and body fat percentage [15.8% (4.2)→12.6 (4.5)%] declined significantly compared to preintervention (all P<0.001), as did systolic blood pressure (P=0.002) and mean blood pressure (P = 0.020). Postintervention body height and free fat mass increased significantly (both P<0.001). Subjects' postintervention lipids including total cholesterol, low-density lipoprotein, high-density lipoprotein, and triglycerides increased significantly (all P<0.001). Inflammatory markers including adiponectin [14.32 (6.68)→31.31 (30.53) μg/mL, P<0.001], interleukin 6 [2.15 (4.81)→2.86 (6.37) pg/mL, P=0.005], and C-reactive protein [1.00 (2.57)→2.30 (4.17) μg/mL, P<0.001] increased significantly postintervention, but not leptin.
Exercise training significantly improves body composition and anti-inflammatory adiponectin levels in lean male adolescents.
体育活动可改善肥胖个体的身体成分和炎症标志物，但对于非肥胖人群了解甚少。
本研究旨在调查台湾瘦体重男性青少年运动与炎症细胞因子之间的关联。
这项干预性研究共纳入了79名来自台湾陆军军官学校的正常体重男性青少年[平均年龄16.8（1.0）岁]。在基线时以及完成为期12周的运动干预计划后测量身体成分和炎症标志物。
与干预前相比，受试者干预后的人体测量指标显著下降，包括腰围[74.6（5.2）→72.6（5.2）厘米]、臀围[92.3（4.1）→89.9（5.0）厘米]、体脂肪量[10.2（3.2）→8.2（3.2）千克]和体脂百分比[15.8%（4.2）→12.6（4.5）%]（均P<0.001），收缩压（P=0.002）和平均血压（P = 0.020）也是如此。干预后身高和去脂体重显著增加（均P<0.001）。受试者干预后的血脂包括总胆固醇、低密度脂蛋白、高密度脂蛋白和甘油三酯显著增加（均P<0.001）。炎症标志物包括脂联素[14.32（6.68）→31.31（30.53）微克/毫升，P<0.001]、白细胞介素6[2.15（4.81）→2.86（6.37）皮克/毫升，P=0.005]和C反应蛋白[1.00（2.57）→2.30（4.17）微克/毫升，P<0.001]在干预后显著增加，但瘦素未增加。
运动训练可显著改善瘦体重男性青少年的身体成分和抗炎脂联素水平。
