Qin Xinyuan, Zhang Shaochun, Gao Lei, Yin Yefeng, Liu Ning, Wang Jiangning
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2014 Aug;28(8):1047-50.
To summarize the research progress of severed limb preservation by perfusion and to analyze difference in effect of severed limb preservation by different perfusate.
The domestic and foreign related literature about severed limb preservation by perfusion was extensively reviewed and analyzed.
Currently the main perfusate includes organ perfusate, free radical scavengers, energy mixture, blood substitutes, and whole blood. They can reduce the skeletal muscle's ischemia-reperfusion injury in different degrees.
Different perfusate can reduce the skeletal muscle's ischemia-reperfusion injury in different degrees, but the best effect of perfusate and personalized preservation method need further study.
总结肢体灌注保存的研究进展，并分析不同灌注液在肢体保存效果上的差异。
广泛查阅并分析国内外有关肢体灌注保存的相关文献。
目前主要的灌注液包括器官灌注液、自由基清除剂、能量合剂、血液代用品和全血。它们能不同程度减轻骨骼肌的缺血再灌注损伤。
不同灌注液能不同程度减轻骨骼肌的缺血再灌注损伤，但最佳灌注液及个体化保存方法仍需进一步研究。
