Brandon L Jerome, Proctor Larry, Cole Calvin L
Ethn Dis. 2014 Autumn;24(4):475-80.
African American women (AAW) have increased odds of developing cardiometabolic (CME) risks and cardiovascular diseases (CVD) compared with European American women (EAW). The influence of obesity on other CME risks and the CVD disparity is unclear. The purpose of our study was to develop a CME index and evaluate the obesity and CME risk index relationships based on race.
A comparative research design was employed in our study as 213 women (132 AAW; 81 EAW) from the Louisiana Delta were evaluated for CME risk clustering patterns by race, based on BMI, dual energy X-ray absorptiometry % body fat and waist conference. Fasting glucose, triglyceride (TC), high density lipoprotein cholesterol (HDL-C), systolic (SBP) and diastolic blood pressure (DBP) were the measured CME risks.
In summary, when the CME indexes were evaluated by obesity classification categories the ones that were CVD risk or near risk for the AAW were SBP and TG. The trend of CME index risk for the EAW was SBP and glucose. The stepwise regression equations indicate that HDL-C and SBP/DBP were the best indicators of the effects of obesity on CME risks in AAW and that SBP/DBP and glucose were the best indicators of CME risks in EAW.
Our results indicate that CME risks as evaluated based on obesity categories are different for AAW than for EAW.
与欧美女性(EAW)相比,非裔美国女性(AAW)患心脏代谢(CME)风险和心血管疾病(CVD)的几率更高。肥胖对其他CME风险和CVD差异的影响尚不清楚。我们研究的目的是制定一个CME指数,并根据种族评估肥胖与CME风险指数之间的关系。
我们的研究采用了比较研究设计,对来自路易斯安那三角洲的213名女性(132名AAW;81名EAW)进行了评估,根据体重指数(BMI)、双能X线吸收法测定的体脂百分比和腰围,按种族划分CME风险聚集模式。测量的CME风险包括空腹血糖、甘油三酯(TC)、高密度脂蛋白胆固醇(HDL-C)、收缩压(SBP)和舒张压(DBP)。
总之,当按肥胖分类类别评估CME指数时,AAW中属于CVD风险或接近风险的是SBP和TG。EAW的CME指数风险趋势是SBP和血糖。逐步回归方程表明,HDL-C和SBP/DBP是肥胖对AAW中CME风险影响的最佳指标,而SBP/DBP和血糖是EAW中CME风险的最佳指标。
我们的结果表明,基于肥胖类别评估的CME风险在AAW和EAW中有所不同。