Sethukumar P, Heywood R, Narula A
Department of Otolaryngology,St. Mary's Hospital Paddington, Imperial College Healthcare NHS Trust,London,UK.
J Laryngol Otol. 2014 Dec;128(12):1114-6. doi: 10.1017/S0022215114002722. Epub 2014 Nov 24.
Samter's triad is a well described condition manifesting as chronic rhinosinusitis with nasal polyposis, asthma and aspirin intolerance in a non-atopic individual. The underlying mechanism is still to be fully elucidated. However, aural disease has not been widely reported in these patients. In the few reported cases, most patients underwent major surgery with varying degrees of success.
We report two Samter's triad patients with aural involvement. Both were successfully managed by conservative treatment, thus avoiding the need for major surgery. It appears that more Samter's triad patients may have aural disease than previously thought.
We report good outcomes with conservative treatment, which is relevant because aural disease tends to reoccur in these patients.
Samter三联征是一种已被充分描述的病症,表现为非特应性个体的慢性鼻窦炎伴鼻息肉、哮喘和阿司匹林不耐受。其潜在机制仍有待充分阐明。然而,耳部疾病在这些患者中尚未得到广泛报道。在少数已报道的病例中,大多数患者接受了大手术,取得了不同程度的成功。
我们报告了两名患有耳部病变的Samter三联征患者。两人均通过保守治疗成功治愈,从而避免了大手术的需要。似乎患有耳部疾病的Samter三联征患者可能比之前认为的更多。
我们报告了保守治疗的良好效果,这很重要,因为这些患者的耳部疾病往往会复发。