Kamiński Jan P, Pai Ajit, Ailabouni Luay, Park John J, Marecik Slawomir J, Prasad Leela M, Abcarian Herand
Department of Surgery, University of Illinois Metropolitan Group Hospitals, Chicago, Illinois.
Division of Colon and Rectal Surgery, Advocate Lutheran General Hospital, Park Ridge, Illinois.
JSLS. 2014 Oct-Dec;18(4). doi: 10.4293/JSLS.2014.00207.
Limited data are available comparing epidural and patient-controlled analgesia in site-specific colorectal surgery. The aim of this study was to evaluate 2 modes of analgesia in patients undergoing laparoscopic right colectomy (RC) and low anterior resection (LAR).
Prospectively collected data on 433 patients undergoing laparoscopic or laparoscopic-assisted colon surgery at a single institution were retrospectively reviewed from March 2004 to February 2009. Patients were divided into groups undergoing RC (n = 175) and LAR (n = 258). These groups were evaluated by use of analgesia: epidural analgesia, "patient-controlled analgesia" alone, and a combination of both. Demographic and perioperative outcomes were compared.
Epidural analgesia was associated with a faster return of bowel function, by 1 day (P < .001), in patients who underwent LAR but not in the RC group. Delayed return of bowel function was associated with increased operative time in the LAR group (P = .05), patients with diabetes who underwent RC (P = .037), and patients after RC with combined analgesia (P = .011). Mean visual analogue scale pain scores were significantly lower with epidural analgesia compared with patient-controlled analgesia in both LAR and RC groups (P < .001).
Epidural analgesia was associated with a faster return of bowel function in the laparoscopic LAR group but not the RC group. Epidural analgesia was superior to patient-controlled analgesia in controlling postoperative pain but was inadequate in 28% of patients and needed the addition of patient-controlled analgesia.
关于特定部位结直肠手术中硬膜外镇痛与患者自控镇痛对比的数据有限。本研究旨在评估接受腹腔镜右半结肠切除术(RC)和低位前切除术(LAR)患者的两种镇痛模式。
回顾性分析2004年3月至2009年2月在单一机构接受腹腔镜或腹腔镜辅助结肠手术的433例患者的前瞻性收集数据。患者分为接受RC手术组(n = 175)和LAR手术组(n = 258)。这些组通过使用镇痛方法进行评估:硬膜外镇痛、单纯“患者自控镇痛”以及两者联合使用。比较人口统计学和围手术期结果。
硬膜外镇痛与接受LAR手术患者的肠功能恢复加快相关,提前1天恢复(P <.001),但在RC组中并非如此。肠功能恢复延迟与LAR组手术时间延长相关(P =.05)、接受RC手术的糖尿病患者相关(P =.037)以及接受RC手术且联合镇痛的患者相关(P =.011)。在LAR组和RC组中,与患者自控镇痛相比,硬膜外镇痛的平均视觉模拟量表疼痛评分显著更低(P <.001)。
硬膜外镇痛与腹腔镜LAR组而非RC组的肠功能恢复加快相关。硬膜外镇痛在控制术后疼痛方面优于患者自控镇痛,但在28%的患者中效果不佳,需要加用患者自控镇痛。