Naganuma Michio, Matsui Hiroki, Fushimi Kiyohide, Yasunaga Hideo
The Department of Radiology, Shonan Izumi Hospital, Kanagawa, Japan.
The Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Heart Vessels. 2016 Jun;31(6):1006-9. doi: 10.1007/s00380-014-0605-5. Epub 2014 Nov 25.
Isolated dissection of an abdominal aortic branch is a rare entity, and previous reports regarding the condition have been based only on small case-series studies. Using a national inpatient database in Japan, we describe the clinical features of patients with isolated celiac, superior mesenteric, splenic, and hepatic artery dissections (ICAD, ISMAD, ISAD, and IHAD). We extracted data on inpatients who were diagnosed with ICAD, ISMAD, ISAD, or IHAD from the Japanese diagnosis procedure combination database, including patients' age and sex, putative risk factors (smoking status and specific comorbidities), treatments (blood transfusion, transcatheter arterial embolization (TAE) and surgical procedures), and outcomes (in-hospital complications and death). Among 18.3 million inpatients in the database between July 2010 and March 2013, we identified 276 ICAD, 715 ISMAD, 23 ISAD and 11 IHAD. The percentage of males was 78-92 %, and the mean age was 54.7-56.8 years. Hypertension was seen in 48-65, and 35-65 % were smokers. Fourteen in-hospital deaths were identified in total. In the ICAD group, splenectomy was performed in one patient and TAE was performed in 26 patients. In the ISMAD group, 16 patients received surgical intervention. Most patients with isolated dissection of an abdominal aortic branch were treated conservatively, while a small percentage required TAE or open surgery. A small proportion of dissections resulted in death.
腹主动脉分支孤立性夹层是一种罕见的疾病,既往关于该疾病的报道仅基于小样本病例系列研究。我们利用日本的全国住院患者数据库,描述了孤立性腹腔干、肠系膜上动脉、脾动脉和肝动脉夹层(ICAD、ISMAD、ISAD和IHAD)患者的临床特征。我们从日本诊断程序组合数据库中提取了被诊断为ICAD、ISMAD、ISAD或IHAD的住院患者的数据,包括患者的年龄和性别、假定的危险因素(吸烟状况和特定合并症)、治疗方法(输血、经导管动脉栓塞术(TAE)和外科手术)以及结局(住院并发症和死亡)。在2010年7月至2013年3月期间数据库中的1830万住院患者中,我们识别出276例ICAD、715例ISMAD、23例ISAD和11例IHAD。男性比例为78%-92%,平均年龄为54.7-56.8岁。48%-65%的患者患有高血压,35%-65%的患者吸烟。总共确定了14例住院死亡病例。在ICAD组中,1例患者接受了脾切除术,26例患者接受了TAE。在ISMAD组中,16例患者接受了手术干预。大多数腹主动脉分支孤立性夹层患者采用保守治疗,而一小部分患者需要TAE或开放手术。一小部分夹层导致了死亡。