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克什米尔地震后精神病症状的发生率及预测因素

Rate and predictors of psychotic symptoms after Kashmir earthquake.

作者信息

Ayub Muhammad, Saeed Khalid, Kingdon David, Naeem Farooq

机构信息

Department of Psychiatry, Queen's University, 191 Portsmouth Avenue, Kingston, ON, Canada,

出版信息

Eur Arch Psychiatry Clin Neurosci. 2015 Sep;265(6):471-81. doi: 10.1007/s00406-014-0561-1. Epub 2014 Nov 25.

Abstract

Psychotic symptoms are more common in general population than validated diagnosis of psychosis. There is evidence to suggest that these symptoms, hallucinations, paranoia, elated mood, thought insertion, are part of a spectrum of psychosis and may have association with the same risk factors that determine development of psychosis. These symptoms have an association with exposure to psychological trauma, post-traumatic stress disorder, anxiety and depression. The aim of this study was to explore the prevalence of psychotic symptoms in the population affected by a natural disaster, earthquake in this case and possible correlates of these symptoms. We conducted a cross-sectional survey of a population sample affected by the disaster, comprising of 1,291 individuals, 18 months after 2005 earthquake in Northern Pakistan and Kashmir to look at the prevalence of these symptoms and their correlates. Screening Instrument for Traumatic Stress in Earthquake Survivors and Self-Reporting Questionnaire and Psychosis Screening Questionnaire were used as tools. We examined association between the symptoms of anxiety, depression, PTSD and psychotic symptoms. We performed logistic regression analysis where hallucinations and delusions were dependent variables and demographic and trauma exposure variables were independent variables. The prevalence of psychotic symptoms ranged between 16.8 and 30.4 %. They were directly correlated with symptoms of post-traumatic stress disorder as well as concurrent symptoms of anxiety and depression. Lower level of education had a strong association in all the regression models. For hallucinations, living in a joint family had a negative association and participation in rescue, history of exposure to previous trauma and past psychiatric history had positive association. Paranoia was associated with female gender. Any psychiatric symptom was associated death of a family member, history of past psychiatric illness and living in a tent at the time of interview. Pattern of association of psychotic symptoms is consistent with prior literature and can be understood in the light of stress vulnerability model.

摘要

在普通人群中,精神病性症状比经过验证的精神病诊断更为常见。有证据表明,这些症状,如幻觉、偏执、情绪高涨、思维插入,是精神病谱系的一部分,可能与决定精神病发展的相同风险因素有关。这些症状与心理创伤暴露、创伤后应激障碍、焦虑和抑郁有关。本研究的目的是探讨受自然灾害(本案例为地震)影响人群中精神病性症状的患病率及其可能的相关因素。我们对受灾害影响的人群样本进行了横断面调查,该样本由1291人组成,在2005年巴基斯坦北部和克什米尔地震18个月后进行,以了解这些症状的患病率及其相关因素。使用地震幸存者创伤应激筛查工具、自填问卷和精神病筛查问卷作为工具。我们研究了焦虑、抑郁、创伤后应激障碍症状与精神病性症状之间的关联。我们进行了逻辑回归分析,其中幻觉和妄想为因变量,人口统计学和创伤暴露变量为自变量。精神病性症状的患病率在16.8%至30.4%之间。它们与创伤后应激障碍症状以及焦虑和抑郁的并发症状直接相关。在所有回归模型中,较低的教育水平都有很强的关联。对于幻觉,生活在大家庭中有负相关,参与救援、既往创伤暴露史和既往精神病史有正相关。偏执与女性性别有关。任何精神症状都与家庭成员死亡、既往精神疾病史以及访谈时住在帐篷里有关。精神病性症状的关联模式与先前的文献一致,并且可以根据应激易感性模型来理解。

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